Title:Hidradenoma Papilliferum of Vulva Simulating Vulval Carcinoma: A Case Report
Volume: 21
Issue: 1
Author(s): Naina Kumar*, Immanuel Pradeep, Mishu Mangla and Subhrajyoti Roy
Affiliation:
- Department of Obstetrics and Gynecology, All India Institute of Medical Sciences, Bibinagar-508126, Hyderabad
Metropolitan Region, Telangana, India
Keywords:
Benign tumor, hidradenoma, labia majora, pruritis, Vulva, sweat glands.
Abstract:
Purpose: Vulval Hidradenoma papilliferum is a rare benign tumor originating from apocrine
sweat glands. They present as a solid solitary nodule of 1-2 cm on the inner margin of labia majora.
Since they are not commonly encountered, their diagnosis is usually difficult and puzzles with
other conditions such as benign and malignant lesions of the skin, vulva, and perineum. The present
case report highlights one such case of vulval Hidradenoma papilliferum in a postmenopausal woman
diagnosed after a histopathological examination of an excised lesion.
Case Presentation: A 55-year-old P2L2 postmenopausal woman presented to the Gynecology outpatient
department complaining of itching over the vulval region for 3-4 months. There was no associated
bleeding or discharge per vaginum. On local examination, a single nodular, hypopigmented,
non-tender, ulcerative lesion was seen over the right labia majora of size 1x2 cm. It was solid in consistency.
The lesion was excised and sent for histopathological examination, which revealed a wellcircumscribed
subepithelial tumor composed of delicate, complex branching papillae and glandular
elements lined by columnar epithelial secretory cells and myoepithelial cells suggestive of hidradenoma
papilliferum.
Major Findings: The diagnosis of hidradenoma papilliferum is usually made on surgical excision
and histopathological evaluation of lesions. Hidradenoma papilliferum is difficult to diagnose clinically
as it mimics other benign and malignant gynecological and cutaneous diseases.
Conclusion: Hence, hidradenoma papilliferum should be kept as a differential in diagnosing women
with solitary asymptomatic nodules in the anogenital region.
