Title:Intravaginal Delivery of Herbal Pharmaceutical Interventions for Uncomplicated UTIs in Women
Volume: 21
Issue: 2
Author(s): Nidhi Semwal, Deepika Joshi*, Priya Sharma, Archana Rautela and Bhavana Singh
Affiliation:
- School of Pharmacy,
Graphic Era Hill University, Clement Town Dehradun, Uttarakhand, India
Keywords:
Uncomplicated urinary tract infection, intravaginal, herbal, bacteria, diabetes, kidney transplant.
Abstract:
Background: Urinary tract infection (UTIs) is the most common infection in women affecting
approximately 75% of women worldwide during their pregnancy, and in pre and postmenopausal
women. Typical symptoms include urinary frequency, urgency, suprapubic discomfort, and
dysuria.
Method: An introduction to the epidemiology of UTIs and detailed herbal nanoformulation treatment
approach through novel intravaginal route is intended through this narrative review. UTIs
are associated with significant morbidity and mortality, and they affect the quality of life of the affected
patients. Multidrug-resistant bacteria and recurrent UTIs are becoming more common. Development
of resistance, adverse effects of antibiotics, and other associated problems lead to establishing
the research framework to find out the alternative approaches in controlling UTIs. Antibiotic-
free treatments for uncomplicated urinary tract infections UTIs should be used, saving drugs
for severe infections. Herbal medication might be used instead of antibiotics for uncomplicated
UTIs, in addition to analgesics for purely symptomatic treatment.
Conclusion: This review identifies the pathophysiology of UTI, distinguish the intravaginal route
as an alternative to oral delivery route, summarizes the management of urinary tract infections and
highlights the anti-uropathogenic and anti-bactericidal effects of herbal approaches to prevent or
treat urinary tract infections.
