Wide-ranging Study on Synthesis and Biological Evaluation of 1, 2, 3-triazole

Title:Wide-ranging Study on Synthesis and Biological Evaluation of 1, 2, 3-triazole

Volume: 20 Issue: 7

Author(s): Anshu Dudhe*, Rupesh Dudhe, Renuka Mahajan, Neha Pathak, Vaibhav Uplanchiwar and Mohammad Hashim Mansoori

Affiliation:

• Department of Pharmacy, Nagpur College of Pharmacy, Wanadongri, Nagpur, Maharashtra, 441110, India

Keywords: 1, 2, 3-traizole, antimicrobial, anticonvulsant, analgesic, antimalarial, heterocyclic compounds.

Abstract: 1, 2, 3-traizole is five-membered heterocyclic compounds having three nitrogen at 1, 2 and 3 positions. 1, 2, 3-triazoles are important five-membered heterocyclic scaffolds due to their widespread biological activities. 1, 2, 3-triazole derivative can be readily obtained in good to excellent yields through click chemistry, 1, 3-dipolar cycloaddition, Metal Catalysed azide-alyne cycloaddition method. 1, 2, 3-triazoles showed various biological activities, such as antiinflammatory, anticonvulsant, antineoplastic, antimicrobial, analgesic, antimalarial, antiviral, antiproliferative, and anticancer activities. The objective of this review is to synthesize pharmacological activity of 1,2,3-triazole derivatives documented in recent literature.

Cite this article as:

Dudhe Anshu*, Dudhe Rupesh, Mahajan Renuka, Pathak Neha, Uplanchiwar Vaibhav and Mansoori Hashim Mohammad, Wide-ranging Study on Synthesis and Biological Evaluation of 1, 2, 3-triazole, Current Bioactive Compounds 2024; 20 (7) : e050124225297 . https://dx.doi.org/10.2174/0115734072275678231214051003