Abstract
Background: Preoperative T-staging is essential for planning optimal treatment and care for colorectal cancer (CRC).
Objective: To evaluate the accuracy of Dual-energy CT (DECT) in preoperative T-staging of CRC.
Methods: The clinical data and DECT images of 37 patients with 39 CRC lesions were retrospectively analyzed. The performance of the DECT quantitative parameters in CRC T-staging was evaluated. Postoperative pathologic results were used as a gold standard. Receiver operating characteristic curves were used to assess the diagnostic efficacy of DECT parameters. P < 0.05 was deemed significant.
Results: The overall accuracy of T-staging by DECT was 76.9%. The DECT parameters were significantly different between the T3 pericolic fat stranding, T4a pericolic fat stranding, and normal pericolic fat stranding. Arterial phase λHU had the best diagnostic performance with a cut-off value of ≥0.967, resulting in a 70.6% sensitivity and a 100% specificity in differentiating between T3 and T4a stages of CRC.
Conclusion: DECT has high accuracy in the T-staging of CRC. Arterial phase λHU has the best diagnostic performance in differentiating between T3 and T4a stages of CRC.
Keywords: Neoplasm staging, Arteries, Colorectal neoplasms, Lymph nodes, Colorectal cancer, Computed tomography.
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