Title:Comparison of the Effectiveness of Endometrial Scratching in Follicular and Luteal Phases in Pregnancy Rate of Frozen Embryo Transfer Candidate Women
Volume: 21
Issue: 1
Author(s): Shamim Pilehvar*, Marzieh Autoogar, Faryar Hakemzadeh, Amin Doostiiranid and Samar Moghadami
Affiliation:
- Department of Gynecology, Clinical Research Development Unit of Fatemieh Hospital, Hamadan University of Medical
Sciences, Hamadan, Iran
Keywords:
Endometrial injury, follicular phase, luteal phase, pregnancy rate, in vitro fertilization (IVF), endometrial scratching.
Abstract:
Background: Endometrial scratching (ES) has been reported as a strategy to improve
the outcome of IVF. Considering that the follicular phase and luteal phase have their specific characteristics
and hormonal secretions, we investigated whether scratching in different phases affects
a woman's chances of becoming pregnant following frozen embryo transfer.
Methods: A total of 300 frozen embryo transfer candidate women with normal cavities and good
embryo quality were randomly divided into two groups: Group A with ES in the follicular phase
and group B with ES in the luteal phase. In both groups, endometrial scratching was performed before
IVF. The rate of pregnancy and baseline characteristics, such as age, education, and embryo
quality, were compared between the two groups.
Results: Our results showed no significant differences in baseline characteristics between the
groups. Furthermore, no significant differences were observed between the women who underwent
ES in the follicular phase and those in the luteal phase for the outcome of IVF and chemical
or clinical pregnancies.
Conclusion: ES in different phases of the cycle preceding frozen embryo transfer did not affect
the outcome of pregnancy.
