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Review Article

Targeted Delivery Strategies of Herbal-Based Nanogels: Advancements and Applications

Author(s): Sudhanshu Mishra, Sonali Jayronia, Lalit Kumar Tyagi and Kanchan Kohli*

Volume 24, Issue 16, 2023

Published on: 10 November, 2023

Page: [1260 - 1270] Pages: 11

DOI: 10.2174/0113894501275800231103063853

Price: $65

Abstract

The objective of this review is to thoroughly investigate herbal nano gels as a promising drug delivery approach for the management of various chronic and acute disorders. Herbal nano gels are a novel and promising drug delivery technique, offering special benefits for better therapeutic efficacy. This review offers a comprehensive analysis of the herbal nano gels with a particular emphasis on their evaluation concerning conventional dosage forms, polymer selection criteria, drug release mechanisms, and applications. The comparison study demonstrates that herbal nano gels have different benefits over conventional dose forms. In the areas of oral administration for improved bioavailability and targeted delivery to the gastrointestinal tract, topical drug delivery for dermatological conditions, and targeted delivery strategies for the site-specific treatment of cancer, inflammatory diseases, and infections, they demonstrate encouraging results in transdermal drug delivery for systemic absorption. A promising platform for improved medication delivery and therapeutic effectiveness is provided by herbal nanogels. Understanding drug release mechanisms further contributes to the controlled and sustained delivery of herbal therapeutics. Some of the patents are discussed and the comparative analysis showcases their superiority over conventional dosage forms, and the polymer selection criteria ensure the design of efficient and optimized formulations. Herbal-based nano gels have become a potential approach for improving drug administration. They provide several advantages such as better stability, targeted delivery, and controlled release of therapeutic components. Herbal nano gels are a promising therapeutic approach with the ability to combat a wide range of conditions like cancer, wound healing and also improve patient compliance.

Keywords: Nanogels, Polymer, herbal, diffusion, bioimaging, Targeted drug delivery.

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