Title:Targeted Delivery Strategies of Herbal-Based Nanogels: Advancements
and Applications
Volume: 24
Issue: 16
Author(s): Sudhanshu Mishra, Sonali Jayronia, Lalit Kumar Tyagi and Kanchan Kohli*
Affiliation:
- Lloyd Institute of Management and Technology, Plot No.-11, Knowledge Park-II, Greater Noida, Uttar
Pradesh-201306, India
Keywords:
Nanogels, Polymer, herbal, diffusion, bioimaging, Targeted drug delivery.
Abstract: The objective of this review is to thoroughly investigate herbal nano gels as a promising
drug delivery approach for the management of various chronic and acute disorders. Herbal
nano gels are a novel and promising drug delivery technique, offering special benefits for better
therapeutic efficacy. This review offers a comprehensive analysis of the herbal nano gels with a
particular emphasis on their evaluation concerning conventional dosage forms, polymer selection
criteria, drug release mechanisms, and applications. The comparison study demonstrates that herbal
nano gels have different benefits over conventional dose forms. In the areas of oral administration
for improved bioavailability and targeted delivery to the gastrointestinal tract, topical drug delivery
for dermatological conditions, and targeted delivery strategies for the site-specific treatment
of cancer, inflammatory diseases, and infections, they demonstrate encouraging results in transdermal
drug delivery for systemic absorption. A promising platform for improved medication delivery
and therapeutic effectiveness is provided by herbal nanogels. Understanding drug release
mechanisms further contributes to the controlled and sustained delivery of herbal therapeutics.
Some of the patents are discussed and the comparative analysis showcases their superiority over
conventional dosage forms, and the polymer selection criteria ensure the design of efficient and optimized
formulations. Herbal-based nano gels have become a potential approach for improving
drug administration. They provide several advantages such as better stability, targeted delivery,
and controlled release of therapeutic components. Herbal nano gels are a promising therapeutic approach
with the ability to combat a wide range of conditions like cancer, wound healing and also
improve patient compliance.
