Title:A Review on Nano/Microfluidic Devices for Cell Isolation Techniques:
Recent Progress and Advances
Volume: 20
Issue: 6
Author(s): Hamid Reza Garshasbi and Seyed Morteza Naghib*
Affiliation:
- Nanotechnology Department, School of Advanced Technologies, Iran University of Science and Technology, P.O. Box
16846-13114, Tehran, Iran
Keywords:
Nano/microfluidics, cell isolation, single-molecule, biological assessment, droplet, biochemical analysis.
Abstract: Micro/nanofluidic devices and systems have gained increasing interest in healthcare
applications over the last few decades because of their low cost and ease of customization, with
only a small volume of sample fluid required. Many biological queries are now being addressed
using various types of single-molecule research. With this rapid rise, the disadvantages of these
methods are also becoming obvious. Micro/nanofluidics-based biochemical analysis outperforms
traditional approaches in terms of sample volume, turnaround time, ease of operation, and
processing efficiency. A complex and multifunctional micro/nanofluidic platform may be used
for single-cell manipulation, treatment, detection, and sequencing. We present an overview of
the current advances in micro/nanofluidic technology for single-cell research, focusing on cell
capture, treatment, and biochemical analyses. The promise of single-cell analysis using micro/
nanofluidics is also highlighted.
