A Glance on Nanovaccine: A Potential Approach for Disease Prevention

Akash      Garg; Rutvi      Agrawal; Himansu      Chopra; Talever      Singh; Ramkumar      Chaudhary; Abhishek      Tankara
doi:10.2174/0113892010254221231006100659
Abstract

There are several vaccines available for preventing various bacterial and viral infections, but still, there are many challenges that require the development of noninvasive, more efficient, and active vaccines. The advancement in biotechnological tools has provided safer antigens, such as nucleic acids, proteins etc., but due to their lower immunogenic property, adjuvants of stronger immune response are required. Nanovaccines are effective vaccines when compared with conventional vaccines as they can induce both Humoral and cell-mediated immune responses and also provide longer immunogenic memory. The nanocarriers used in vaccines act as adjuvant. They provide site-specific delivery of antigens and can be used in conjugation with immunostimulatory molecules for enhancing adjuvant therapy. The nanovaccines avoid degrading cell pathways and provide effective absorption into blood vessels. The higher potential of nanovaccines to treat various diseases, such as acquired immuno deficiency syndrome, cancer, tuberculosis, malaria and many others, along with their immunological mechanisms and different types, have been discussed in the review.
Keywords: Vaccine, nanovaccine, immune response, infectious diseases, humoral, cell-mediated.
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DOI https://dx.doi.org/10.2174/0113892010254221231006100659	Print ISSN 1389-2010
Publisher Name Bentham Science Publisher	Online ISSN 1873-4316
Current Pharmaceutical Biotechnology

A Glance on Nanovaccine: A Potential Approach for Disease Prevention

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Current Pharmaceutical Biotechnology

A Glance on Nanovaccine: A Potential Approach for Disease Prevention

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