Title:Current Trends on Innovative Technologies in Topical Wound Care for
Advanced Healing and Management
Volume: 16
Issue: 3
Author(s): Qazi Saifullah and Abhishek Sharma*
Affiliation:
- Department of Pharmacy, University Institute of Pharma Sciences, Chandigarh University, Gharuan, Punjab, 140413, India
Keywords:
Wound healing, wound dressings, chronic wounds, tissue engineering, stem cells, nano-therapeutics, 3D-bio-printing.
Abstract:
Objectives: To investigate critically traditional and modern techniques for cutaneous
wound healing and to provide comprehensive information on these novel techniques to encounter
the challenges with the existing wound healing methods.
Significance: The financial burden and mortality associated with wounds is increasing, so managing
wounds is essential. Traditional wound treatments include surgical and non-surgical
methods, while modern techniques are advancing rapidly. This review examines the various
traditional and modern techniques used for cutaneous wound healing.
Key Findings: Traditional wound treatments include surgical techniques such as debridement,
skin flaps, and grafts. Non-surgical treatments include skin replacements, topical formulations,
scaffold-based skin grafts, and hydrogel-based skin dressings. More modern techniques include
using nanoparticles, growth factors, and bioactive substances in wound dressings. Bioengineered
skin substitutes using biomaterials, cells, and growth factors are also being developed.
Other techniques include stem cell therapy, growth factor/cytokine therapy, vacuum-assisted
wound closure, and 3D-printed/bio-printed wound dressings.
Conclusion: Traditional wound treatments have been replaced by modern techniques such as
stem cell therapy, growth factor/cytokine therapy, vacuum-assisted wound closure, and bioengineered
skin substitutes. However, most of these strategies lack effectiveness and thorough
evaluation. Therefore, further research is required to develop new techniques for cutaneous
wound healing that are effective, cost-efficient, and appealing to patients.