Title:Emerging Insights and Global Trends in the Relationship between Selenium
and Thyroid Diseases: A Bibliometric Analysis
Volume: 24
Issue: 7
Author(s): Yuqing Wu, Tiantian Cai, Yuan Tao, Jing Zhao and Jinan Zhang*
Affiliation:
- Department of Endocrinology
& Rheumatology, Shanghai University of Medicine & Health Sciences Affiliated Zhoupu Hospital, Shanghai,
201318, China
- Shanghai
University of Traditional Chinese Medicine, Shanghai, 201203, China
Keywords:
Bibliometric analysis, selenium, thyroid disease, insight, trend, VOSviewer, CiteSpace.
Abstract:
Objective: Selenium, a significant trace element needed by the human body, is closely
related to thyroid. Therefore, this study aimed to explore the status of selenium and thyroid diseases,
analyze emerging insights, and predict future trends.
Methods: Literature on selenium and thyroid included in the core database of Web of Science
from January 1992 to October 2022 was retrieved. CiteSpace and VOSviewer software were used
for visual analysis in terms of publication, author, country, institution, co-citation, and keywords.
Results: A total of 1,142 works of literature were included after the screening, and the annual publication
showed a fluctuating upward trend. The country and the institution with the highest publication
volume were the United States and Charité Universitätsmedizin Berlin, respectively. In
terms of authors, Schomburg L has formed a cooperative network and has published the largest
number of papers and made great contributions in this field. The biggest cluster of keywords was
trace elements, and the hot keywords in recent years were oxidative stress, Hashimoto's thyroiditis,
cadmium, copper, etc.
Conclusion: This paper analyzes the current status, insights, and trends of the studies on selenium
and thyroid diseases by the method of bibliometrics and delivers ideas and methods for subsequent
research in this field. The therapeutic effect of selenium on Hashimoto's thyroiditis is controversial
and needs further research, and oxidative stress is also a research hotspot in this field. The crossstudy
of multiple trace elements and diseases may be the development trend in the future.
