Title:A Comparison of Colour Doppler Ultrasound and 2D Ultrasound as Promising
Prediction Methods for the Treatment effect of Patients with Advanced Cervical
Cancer
Volume: 20
Author(s): Beibei Dai*
Affiliation:
- Department of Ultrasound, Obstetrics and Gynecology Hospital of Fudan University, 419 Fangxie Road, Shanghai 200,011, China
Keywords:
Two-dimensional ultrasound, Colour doppler ultrasound, Cervical cancer, chemo-radiotherapy, angiogenesis.
Abstract:
Background:
A number of studies have evaluated the effect of colour Doppler ultrasound in patients with cervical cancer.
Objective: This study aims to evaluate the efficacy of colour Doppler ultrasound and two-dimensional ultrasound of monitoring patients with
cervical cancer.
Methods:
Colour Doppler ultrasound (Experimental group) and two-dimensional ultrasound (Control group) are used to monitor cervical cancer and assess
the treatment effects. PFS, CI, HR, DCR, ORR, PR, SD, PD, ROD, sensitivity, and specificity, accuracy between the two groups were collected
and analyzed.
Results:
A total of 50 patients are included in this study, and the results show that PFS (Experimental group (EG) 5.8±2.2 versus Control group (CG)
6.1±2.6), CI (EG 20% versus CG 16%), HR (EG0.31±0.18 versus CG 0.36±0.21), DCR (EG 80% versus CG 84%), ORR(EG 28% versus CG
36%), PR (EG 16% versus CG 20%), SD (EG 48% versus CG 56%), PD (EG 12% versus CG 16%) (EG 12% versus CG 16%), ROD(EG 44%
versus CG 52%) between the two groups are >0.05, and the values of sensitivity (EG 75.6% versus CG 40.2%), specificity (EG 78.4% versus CG
43.3%), and accuracy(EG 80.5% versus CG 41.4%) between the two groups are<0.05.
Conclusion:
Both Colour Doppler ultrasound and two-dimensional ultrasound are effective methods to evaluate the efficacy of concurrent chemo-radiotherapy
in patients with cervical cancer.
