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摘要
生物活性肽是一类很有前途的治疗阿尔茨海默病和脑部疾病的药物。这些多肽来源于天然存在的蛋白质,并已被证明具有多种有益的特性。它们可以调节神经递质系统,减少炎症,提高认知能力。此外,生物活性肽具有靶向参与阿尔茨海默病和脑部疾病发病机制的特定分子途径的潜力。例如,肽已被证明与淀粉样蛋白- β相互作用,淀粉样蛋白- β是阿尔茨海默病中发现的淀粉样斑块的主要成分,并已被证明可以减少其在大脑中的积累。此外,已经发现肽可以调节谷氨酸受体的活性,这对记忆和学习很重要,也可以抑制参与形成有毒淀粉样蛋白聚集体的酶的活性。最后,生物活性肽具有减少氧化应激和炎症的潜力,这是许多神经系统疾病的两个主要组成部分。这些肽可以单独使用或与传统的药物治疗联合使用,以改善与阿尔茨海默氏症和脑部疾病相关的疾病的管理。
关键词: 生物活性肽,天然蛋白质,有益特性,阿尔茨海默氏症和脑部疾病,传统药物治疗。
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