Title:Potential and Harmful Effects of Titanium Dioxide Nanoparticle on Health: A Brief Note
Volume: 10
Issue: 1
Author(s): Nikitha Shalom Richard*
Affiliation:
- Faculty of Allied Health Sciences, Chettinad Hospital and Research Institute, Chettinad Academy of Research and
Education, Kelambakkam, Tamilnadu, 603103, India
Keywords:
Titanium dioxide nanoparticle, advantages, toxicity, size, methods, application.
Abstract: Titanium dioxide nanoparticles (TiO2 NPs) are formed in vast amounts worldwide for usage
in several applications. They possess excellent photocatalytic properties, high chemical stability,
and a wide bandgap, making them highly effective in environmental remediation and solar energy
conversion. TiO2 nanoparticles exhibit biocompatibility, allowing their utilization in biomedical uses,
such as molecular imaging, drug delivery, and tissue engineering. Chemical methods, such as hydrothermal,
sol-gel, and chemical vapor deposition, provide versatility in controlling nanoparticle size,
morphology, and crystallinity. They offer relatively lower production costs, scalability, and the ability
to incorporate dopants or functionalize the nanoparticle surface. Their small size and large surface area-
to-volume ratio enable enhanced reactivity and surface functionality, facilitating their incorporation
into composite materials and surface coatings for improved performance. Regarding the potential toxicity
of TiO2 nanoparticles, the bulk form of TiO2 is considered safe for human consumption, but the
reduced size of nanoparticles raises concerns about their potential adverse effects. TiO2 nanoparticles
strongly depend on factors, such as particle size, surface modifications, exposure route, and duration.
Therefore, continued research is essential to gain a comprehensive understanding of the toxicity
mechanisms and develop strategies to mitigate any potential adverse effects, ensuring the safe and responsible
utilization of TiO2 nanoparticles in different fields.
