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当代阿耳茨海默病研究

Editor-in-Chief

ISSN (Print): 1567-2050
ISSN (Online): 1875-5828

Research Article

与认知功能相关的多重感觉障碍:两项全国性的横断面研究

卷 20, 期 5, 2023

发表于: 07 September, 2023

页: [360 - 370] 页: 11

弟呕挨: 10.2174/1567205020666230816090903

价格: $65

Open Access Journals Promotions 2
摘要

介绍:感觉障碍(SI,包括视觉、听觉、嗅觉和味觉障碍)与年龄相关的认知功能单独相关。人们对它们与认知功能的关联知之甚少。 方法:我们纳入了来自全国健康和营养检查调查(NHANES, 2011-2014)的2931名参与者(平均年龄69.1岁)和来自全国健康访谈调查(NHIS, 2021)的10785名参与者(平均年龄70.2岁)。视觉、听觉、嗅觉和味觉功能状况以结构化问卷自述。在NHANES中,认知功能是通过一系列测试客观测量的,包括记忆力、语言流畅性和处理速度。NHIS参与者回答了一个关于主观认知抱怨(SCC)的单一问题。我们使用回归模型来评估NHANES中认知域z分数(线性回归)和NHIS中SCC(逻辑回归)与总数和个体感觉障碍的关系。 结果:更多的SI与较差的特定领域认知功能相关(均p趋势<0.05),包括记忆力(每增加一个SI = -0.12, 95%可信区间:-0.17至-0.08),语言流畅性(-0.05,-0.10至-0.01)和处理速度(-0.13,-0.16至-0.09)。在NHIS中,每增加一个SI, SCC的几率就会增加96%。我们还观察到感觉障碍(嗅觉障碍除外)与特定认知领域的独立关联。此外,每个个体SI与SCC的较高几率相关(比值比从1.30到1.78不等)。 结论:更多的SI与更差的认知功能和更高的SCC几率有关。

关键词: 感觉障碍,认知功能障碍,视觉障碍,听力障碍,嗅觉障碍,味觉障碍,脑老化,横断面研究。

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