Title:Development of Oral Bio-banks Past, Present and Future; Challenges and
Opportunities
Volume: 24
Issue: 1
关键词:
口腔生物库，口腔疾病，口腔肿瘤学，基因组学，知识产权，专利。
摘要: Biobank involves collecting, processing, storing, and organizing biosamples, along with
relevant personal and health information such as medical history, family records, genetics data, and
lifestyle details, for medical research and clinical care. Oral biobanking is a recently evolved field
alongside the rising of precision medicine due to recent research findings in oral oncology and other
oral complaints, namely caries and periodontal disease. The common samples in oral biobanks are matured
and primary teeth, dental pulp cells, oral biopsies, oral rinses, saliva, and swabs from the buccal
region. Moreover, biobank should not conceive of as a static collection of samples and data but as a
dynamic resource for developing novel techniques that meet current scientific demands through international
networking. However, the major bottlenecks associated with oral biobanks are privacy, processing
of samples, normalization of data, extended durability of interest markers of banked samples,
and financial sustainability of biobanks. Thus in this correspondence, we argue that an alternative approach
is urgently needed to protect the interests of many stakeholders.
