Development of Oral Bio-banks Past, Present and Future; Challenges and Opportunities

Title:Development of Oral Bio-banks Past, Present and Future; Challenges and Opportunities

Volume: 24 Issue: 1

Author(s): Gangadhar Baniekal Hiremath, Kondragunta Omkarbabu, Madhavi Hemant Kokate, Baskar Venkidasamy*, Murugesan Krishnan and Arun Murugaiyan

Affiliation:

• Department of Oral and Maxillofacial Surgery, Saveetha Dental College and Hospitals, Saveetha Institute of Medical and Technical Sciences (SIMATS), Saveetha University, Chennai, India

Keywords: Oral bio-bank, oral diseases, oral oncology, genomics, intellectual property rights, patent.

Abstract: Biobank involves collecting, processing, storing, and organizing biosamples, along with relevant personal and health information such as medical history, family records, genetics data, and lifestyle details, for medical research and clinical care. Oral biobanking is a recently evolved field alongside the rising of precision medicine due to recent research findings in oral oncology and other oral complaints, namely caries and periodontal disease. The common samples in oral biobanks are matured and primary teeth, dental pulp cells, oral biopsies, oral rinses, saliva, and swabs from the buccal region. Moreover, biobank should not conceive of as a static collection of samples and data but as a dynamic resource for developing novel techniques that meet current scientific demands through international networking. However, the major bottlenecks associated with oral biobanks are privacy, processing of samples, normalization of data, extended durability of interest markers of banked samples, and financial sustainability of biobanks. Thus in this correspondence, we argue that an alternative approach is urgently needed to protect the interests of many stakeholders.

Cite this article as:

Hiremath Baniekal Gangadhar, Omkarbabu Kondragunta, Kokate Hemant Madhavi, Venkidasamy Baskar*, Krishnan Murugesan and Murugaiyan Arun, Development of Oral Bio-banks Past, Present and Future; Challenges and Opportunities, Current Gene Therapy 2024; 24 (1) . https://dx.doi.org/10.2174/1566523223666230801090355