The Prospects of Phytomedicines and Nanomedicines to Treat Leishmaniasis: A Comprehensive Review

Title:The Prospects of Phytomedicines and Nanomedicines to Treat Leishmaniasis: A Comprehensive Review

Volume: 16 Issue: 3

Author(s): Rajan Swami*Keshav Aggarwal

Affiliation:

• Department of Pharmaceutics, Chitkara College of Pharmacy, Chitkara University, Punjab, India

Keywords: Nanoparticles, phytomedicines, herbal medicines, neglected diseases, leishmaniasis, neglected tropical diseases (NTDs).

Abstract: The global shift in lifestyle has prompted health agencies to redirect their focus from poverty-related diseases to the emergence of lifestyle diseases prevalent in privileged regions. As a result, these diseases have been labeled as "neglected diseases," receiving limited research attention, funding, and resources. Neglected Tropical Diseases (NTDs) encompass a diverse group of vector-borne protozoal diseases that are prevalent in tropical areas worldwide. Among these NTDs is leishmaniasis, a disease that affects populations globally and manifests as skin abnormalities, internal organ involvement, and mucous-related abnormalities. Due to the lack of effective and safe medicines and vaccines, it is crucial to explore alternative resources. Phytomedicine, which comprises therapeutic herbal constituents with anti-leishmanial properties, holds promise but is limited by its poor physicochemical properties. The emerging field of nanomedicine has shown remarkable potential in revitalizing the anti-leishmanial efficacy of these phytoconstituents. In this investigation, we aim to highlight and discuss key plant constituents in combination with nanotechnology that have been explored in the fight against leishmaniasis.

Cite this article as:

Swami Rajan*, Aggarwal Keshav, The Prospects of Phytomedicines and Nanomedicines to Treat Leishmaniasis: A Comprehensive Review, Current Drug Research Reviews 2024; 16 (3) . https://dx.doi.org/10.2174/2589977515666230725105141