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Current Respiratory Medicine Reviews

Editor-in-Chief

ISSN (Print): 1573-398X
ISSN (Online): 1875-6387

Research Article

Post and During SARS-Cov-2 Syndrome in Children

Author(s): Niloofar Karimi Afshar, Reza Sinaei, Ali Hoseininasab, Saeedeh Parvaresh, Maryam Ahmadipour, Fatemeh Karami Robati, Maedeh Jafari*, Sedigheh Jalali and Mohammad Ali Jafari

Volume 19, Issue 3, 2023

Published on: 09 August, 2023

Page: [234 - 238] Pages: 5

DOI: 10.2174/1573398X19666230720114556

Price: $65

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Abstract

Background: SARS-Cov-2 is a highly infectious and contagious disease caused by a coronavirus called severe coronavirus-acute respiratory syndrome (SARS-CoV2). Children with SARS-CoV-2 infection are often asymptomatic or have relatively mild symptoms, often with cough and fever. Today, despite High value information about the manifestations and risk factors for SARS-CoV-2, there is limited information on post-SARS-Cov-2 syndrome, especially in children.

Objective: This study aimed to evaluate the symptoms of SARS-Cov-2 syndrome in children with SARS-Cov-2 in Afzalipour Hospital in Kerman.

Methods: The present descriptive cross-sectional study was performed on 122 children with SARSCov- 2 in 2020-2021. A checklist including information on age, sex, duration of hospitalization, need for admission in intensive care units, clinical symptoms, mortality during or after discharge, underlying illness, and need for readmission was completed by reviewing patient records and interviews. The collected information was entered into SPSS software version 26 for statistical analysis.

Results: The mean age of patients was 46.64±40.39 months. 49.2% of patients were female and 50.8% were male. The most common symptoms were fever (84.4%), weakness (49.2%), cough (34.4%), nausea/vomiting (34.4%), dyspnea (27%), and diarrhea (26.2%). In 122 children, 115 children (94.3%) had symptoms for less than one month, one child had symptoms for one to two months, and 6 children (4.9%) had symptoms for a long duration (more than two months). The most common clinical signs in children with post-SARS-Cov-2 syndrome were weakness (33.3%) and dyspnea (33.3%).

Conclusion: Persistent symptoms of post-SARS-Cov-2 syndrome are less common in children with SARS-Cov-2 disease in Iran.

Keywords: Post Covid-19 syndrome, children, persistent symptoms.

[1]
Khan S, Liu J, Xue M. Transmission of SARS-CoV-2, required developments in research and associated public health concerns. Front Med 2020; 7: 310.
[http://dx.doi.org/10.3389/fmed.2020.00310] [PMID: 32582747]
[2]
Hosseninasab A, Shafiei Bafti M, Ebrahimi S, et al. Coronavirus disease 2019 in children with acute respiratory infection: A study from southeastern Iran. Shiraz E Med J 2020; 21(12): 21.
[http://dx.doi.org/10.5812/semj.108377]
[3]
Singhal T. A review of coronavirus disease-2019 (COVID-19). Indian J Pediatr 2020; 87(4): 281-6.
[http://dx.doi.org/10.1007/s12098-020-03263-6] [PMID: 32166607]
[4]
Li L, Huang T, Wang Y, et al. COVID-19 patients’ clinical characteristics, discharge rate, and fatality rate of meta-analysis. J Med Virol 2020; 92(6): 577-83.
[http://dx.doi.org/10.1002/jmv.25757] [PMID: 32162702]
[5]
Souza TH, Nadal JA, Nogueira RJN, Pereira RM, Brandão MB. Clinical manifestations of children with COVID-19: A systematic review. Pediatr Pulmonol 2020; 55(8): 1892-9.
[http://dx.doi.org/10.1002/ppul.24885] [PMID: 32492251]
[6]
Song W, Li J, Zou N, Guan W, Pan J, Xu W. Clinical features of pediatric patients with coronavirus disease (COVID-19). J Clin Virol 2020; 127: 104377.
[http://dx.doi.org/10.1016/j.jcv.2020.104377] [PMID: 32361323]
[7]
Gupta A, Madhavan MV, Sehgal K, et al. Extrapulmonary manifestations of COVID-19. Nat Med 2020; 26(7): 1017-32.
[http://dx.doi.org/10.1038/s41591-020-0968-3] [PMID: 32651579]
[8]
Carfì A, Bernabei R, Landi F. Gemelli against COVID-19 post-acute care study group. persistent symptoms in patients after acute COVID-19. JAMA 2020; 324(6): 603-5.
[http://dx.doi.org/10.1001/jama.2020.12603] [PMID: 32644129]
[9]
Tenforde MW, Kim SS, Lindsell CJ, et al. Symptom duration and risk factors for delayed return to usual health among outpatients with COVID-19 in a multistate health care systems network-United States, March–June 2020. MMWR Morb Mortal Wkly Rep 2020; 69(30): 993-8.
[http://dx.doi.org/10.15585/mmwr.mm6930e1] [PMID: 32730238]
[10]
van Kampen JJA, van de Vijver DAMC, Fraaij PLA, et al. Duration and key determinants of infectious virus shedding in hospitalized patients with coronavirus disease-2019 (COVID-19). Nat Commun 2021; 12(1): 267.
[http://dx.doi.org/10.1038/s41467-020-20568-4] [PMID: 33431879]
[11]
Datta SD, Talwar A, Lee JT. A proposed framework and timeline of the spectrum of disease due to SARS-CoV-2 infection: Illness beyond acute infection and public health implications. JAMA 2020; 324(22): 2251-2.
[http://dx.doi.org/10.1001/jama.2020.22717] [PMID: 33206133]
[12]
Fernández-de-las-Peñas C, Palacios-Ceña D, Gómez-Mayordomo V, Cuadrado ML, Florencio LL. Defining post-COVID symptoms (post-acute COVID, long COVID, persistent post-COVID): An integrative classification. Int J Environ Res Public Health 2021; 18(5): 2621.
[http://dx.doi.org/10.3390/ijerph18052621] [PMID: 33807869]
[13]
Molteni E, Sudre CH, Canas LS, Bhopal SS, Hughes RC, Antonelli M. Illness duration and symptom profile in a large cohort of symptomatic uk school-aged children tested for SARS-CoV-2. medRxiv 2021; 2021; 21256649.
[http://dx.doi.org/10.1101/2021.05.05.21256649]
[14]
World Health Organization. Global surveillance for human infection with coronavirus disease (COVID-19). Infection-with-novelcoronavirus- (2019-ncov). 2020. Available from: https://www.who.int/publications-detail/global-surveillance-for-human
[15]
Alsharrah D, Alhaddad F, Alyaseen M, et al. Clinical characteristics of pediatric SARS-CoV-2 infection and coronavirus disease 2019 (COVID-19) in Kuwait. J Med Virol 2021; 93(5): 3246-50.
[http://dx.doi.org/10.1002/jmv.26684] [PMID: 33219559]
[16]
Buonsenso D, Munblit D, De Rose C, Sinatti D, Ricchiuto A, Carfi A. Preliminary evidence on long COVID in children. Acta Paediatrica 2021; 110(7): 2208.
[http://dx.doi.org/10.1111/apa.15870]
[17]
Brackel CL, Lap CR, Buddingh EP, Van Houten MA, Van der Sande LJ, Langereis EJ. Pediatric long-COVID: An overlooked phenomenon? Pediatr Pulmonol 2021.
[18]
Sterky E, Olsson-Åkefeldt S, Hertting O, Herlenius E, Alfven T, Rinder MR. Persistent symptoms in swedish children after hospitalisation due to COVID-19. Acta Paediatrica 2021; 110(9): 2578-80.

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