Title:Evaluation of Frequency and Risk Factors of Barotrauma among Patients
with Severe Covid-19 Pneumonia Underwent Non-Invasive Ventilation in
Afzalipour Hospital Kerman
Volume: 19
Issue: 3
Author(s): Behnam Dalfardi, Seyed Mehdi Hashemi Bajgani, Mohammad Javad Najafzadeh, Mohadeseh Shafiei and Mohsen Shafiepour*
Affiliation:
- Clinical Research Development Unit, Afzalipour Hospital‚ Kerman University of Medical Sciences‚ Kerman‚ Iran
Keywords:
Barotrauma, covid-19 pneumonia, acute respiratory distress syndrome, non-invasive ventilation, retrospective study, pneumomediastinum.
Abstract:
Background: Acute respiratory distress syndrome (ARDS) following Covid-19 pneumonia
is an important complication; using non-invasive ventilation (NIV) is one of the best supportive
options available. In the recent Covid-19 pandemic, we have seen a significant increase in barotrauma
incidence following the use of NIV in patients with severe Covid-19 pneumonia.
We aimed to identify the risk factors of barotrauma in patients with Covid-19 pneumonia undergoing
NIV.
Methods: In this retrospective study, all adult patients with severe Covid-19 pneumonia who undergone
NIV and suffered from any form of barotrauma from July to September 2021 in Afzalipour
Hospital, Kerman, Iran were evaluated. Laboratory tests and NIV machine settings were collected
from patients' files. A chi-square test and an independent t-test were used for analytical statistics.
Results: Twenty patients with barotrauma secondary to severe Covid-19 pneumonia were enrolled.
The most common manifestation of barotrauma was pneumomediastinum in 19 patients (95%). No
significant relationship was seen between the occurrence of barotrauma and Laboratory tests. The
mean ± SD Inspiratory Positive Airway Pressure (IPAP) level in passed-away patients (17.8 ± 1.1)
was significantly higher than in recovered patients (13.5 ± 0.5) (p = 0.04).
Conclusion: According to the results of the study, using a low level of IPAP in the ventilator machine
settings of patients with barotrauma secondary to severe Covid-19 pneumonia will reduce the
mortality rate.