Title:Nanotheranostics: The Fabrication of Theranostics with Nanoparticles and their Application to Treat the Neurological Disorders
Volume: 18
Author(s): Astha Singh, Aakriti Patel, Hema Chaudhary, Kiran Yadav and Neha Minocha*
Affiliation:
- Amity Institute of Pharmacy, Amity University, Gurgaon, 122412, Haryana, India
Keywords:
Nanotheranostics, diagnosis, therapeutic modalities, MRI, neurological disorder, theranostics.
Abstract: Background: Theranostics is a method that focuses on providing patient-centred care and is
evolving as a targeted, safe, and effective pharmacotherapy. Nanotheranostics combines diagnosis and
therapeutic modalities that bridge traditional treatment and personalised medicine. Theranostics provides
novel ideas for nanotechnology. This review describes the current state of nanotechnology-based
therapies used to treat neurological illnesses. Some patents on theranostics are also discussed in this review.
Objective: This study aims to provide a more comprehensive review of the diagnosis and therapeutic
properties of nanotheranostics, the present state of nanotechnology-based treatment of neurological disorders,
and the future potential of theranostics.
Methods: The phrase "theranostics" refers to a treatment strategy that integrates therapeutics and diagnostics
to monitor treatment response and enhance drug efficacy and safety. Theranostics is a crucial
component of personalised medicine and calls for significant advancements in predictive medicine. The
term "theranostics" refers to a diagnosis that screens patients for potential adverse drug reactions and
targets drug delivery depending on the test results. Theranostics treats neurological disorders (like brain
tumours (glioma), Parkinson's disease, Alzheimer's disease, and neurovascular diseases). Many review
articles on Google Scholar, PubMed, Google Patents, and Scopus were used to gather information for
this review. Data acquired from many sources was compiled in this review to provide more information
on theranostics.
Results: The role of various nanocarrier systems as theranostic agents for neurological illnesses and the
fabrication of nanomaterials for theranostics are discussed in this article after evaluating a substantial
number of review articles.
Conclusion: The distinctive intrinsic features of nanoparticles make them useful for functionalization
and imaging. Theranostics in nuclear medicine include diagnostic imaging and therapy using the same
molecule that is radiolabeled differently or the same medication at various doses. It is possible to determine
if a patient will benefit from a given treatment by visualising potential targets. Targeted nuclear
therapy has been shown to be beneficial in patients if chosen carefully and has a good safety profile.
