Title:Frequency of Cancer Associated with Children and Adolescents
Volume: 5
Author(s): Zahra Tolou-Ghamari*
Affiliation:
- Nosocomial Infection Research Center, Deputy of Research and Technology, Isfahan University of Medical Sciences, Isfahan, Iran
Keywords:
Frequency, Childhood, Adolescents, Cancer, Leukemia, SEER.
Abstract:
Background:
More than 175,000 new cases of cancer in children are diagnosed every year worldwide.
This study aimed to investigate the recorded cancer frequency in children and adolescents in Isfahan Province, Iran.
As one of the main reasons for death among children and adolescents is reported as cancer with different prevalence worldwide, therefore,
reporting the occurrence of cancers in this population is crucial.
Methods:
Information from the years between 2013 to 2015 related to the Surveillance, Epidemiology, and End Results; (SEER) was collected from the
Isfahan Cancer Registry. The cancer sites studied were defined according to the International Classification of Diseases and recorded by related
topography codes.
Results:
Among all 30,465 registered cancers, there were 582 cases (2%) of cancer, including 57% of children and 43% of adolescents. The mean ± SD age
of patients was 11.5 ± 5.9 years (Min; 1, Max 19). The top four ranked cancers were (n=264; 45%) comprised of; 1) hematopoietic and
reticuloendothelial system (n= 122), 2) secondary and unspecified malignant neoplasm of lymph nodes (n=56), 3) malignant neoplasm of the brain
(n=43) 4), thyroid gland (n=43). Death-reported data was associated with 32% of the total population studied. The neoplasm was reported in 174
cases, which was associated with 95% death.
Conclusion:
This frequency source of children and adolescents cancers could be used for health strategy. The observed variations in the frequency of different
cancers require continuous monitoring and investigation. Therefore, plan of health-system should focus based on greater efforts toward advanced
evidence-based drug therapy in Isfahan, Iran.
