1,3,4-Oxadiazole and Its Analogs: Recently Adopted Synthetic Approaches and Interaction with Targets

Title:1,3,4-Oxadiazole and Its Analogs: Recently Adopted Synthetic Approaches and Interaction with Targets

Volume: 21 Issue: 12

Author(s): Greesh Kumar, Rajnish Kumar*, Avijit Mazumder, Salahuddin and Upendra Kumar

Affiliation:

• Department of Pharmaceutical Chemistry, Noida Institute of Engineering and Technology (Pharmacy Institute), Greater Noida, India

Keywords: 1, 3, 4-oxadiazole, patents, marketed drugs, therapeutic activities, synthetic approaches, target interactions.

Abstract: 1,3,4-Oxadiazole is a five-membered heterocyclic compound with one oxygen, two nitrogen, and two carbon atoms arranged in a ring. Several research reports, patents, and marketed drugs have already established 1,3,4-oxadiazole and its analog as potential molecules having a diverse range of pharmacological activities. In this review, we focused on recently acknowledged straightforward synthesis approaches for 1,3,4-oxadiazole and its analogs. Additionally, interactions of the 1,3,4-oxadiazole derivative with different biological targets (enzymes and receptors) have been described. The present findings discussed in this review analysis will aid researchers in conducting future research on 1,3,4-oxadiazole.

Cite this article as:

Kumar Greesh, Kumar Rajnish*, Mazumder Avijit, Salahuddin and Kumar Upendra, 1,3,4-Oxadiazole and Its Analogs: Recently Adopted Synthetic Approaches and Interaction with Targets, Letters in Drug Design & Discovery 2024; 21 (12) . https://dx.doi.org/10.2174/1570180820666230701000317