Generic placeholder image

Current Diabetes Reviews

Editor-in-Chief

ISSN (Print): 1573-3998
ISSN (Online): 1875-6417

Systematic Review Article

The Need for Early Screening of Diabetic Peripheral Neuropathy and Diabetic Foot in MENA Region: A Review

Author(s): Imen Regai, Meruna Bose*, Animesh Hazari and Praveen Kumar Kandakueti

Volume 20, Issue 3, 2024

Published on: 18 August, 2023

Article ID: e120623217893 Pages: 7

DOI: 10.2174/1573399820666230612141250

Price: $65

conference banner
Abstract

Background: Diabetic peripheral neuropathy (DPN) is the most common complication of diabetes mellitus. Among all complications of DPN, diabetic foot (DF) can cause a myriad of symptoms and impact the quality of life. This study aimed to review the prevalence of DPN and DF in the Middle East and North Africa (MENA) region based on the publications available. This systematic review can be a cornerstone for further research and it summarizes the literature published on the prevalence of DPN and DF for the last two decades in the MENA region.

Methodology: The databases, PubMed, ResearchGate, Scopus, Web of Science, Science Direct, CINAHL, and Cochrane were searched using relevant keywords for the study. Full articles in English since 2000, including keywords “Prevalence”, “Diabetic peripheral neuropathy”, “Diabetic foot”, and “MENA region” were reviewed in two phases. All authors screened the titles and abstracts of the articles individually, which was followed by a screening of full texts. A consensus was made among all the authors for the final selection of the articles based on the eligibility criteria.

Results: Ten selected articles on the prevalence of DPN were reviewed in the first phase of the study, which reported varying prevalence rates among the different countries of the MENA region ranging from 9% to 61%. In the second phase, only two articles on DF prevalence were shortlisted. They reported the prevalence of DF as 4.6% and 18.1% in Jordan and Sudan, respectively.

Conclusion: The prevalence of DPN in the MENA region is varied within a short period of time and the reported prevalence of DF is limited. This study projects a strong need of establishing early screening strategies for DPN and DF to prevent further complications and decrease healthcare burden.

Keywords: Prevalence, diabetes mellitus, diabetic peripheral neuropathy, diabetic foot, MENA region, paraesthesia.

[1]
Punthakee Z, Goldenberg R, Katz P. Definition, classification and diagnosis of diabetes, prediabetes and metabolic syndrome. Can J Diabetes 2018; 42: S10-5.
[http://dx.doi.org/10.1016/j.jcjd.2017.10.003] [PMID: 29650080]
[2]
Wilcox G. Insulin and insulin resistance. Clin Biochem Rev 2005; 26(2): 19-39.
[PMID: 16278749]
[4]
Huang Y, Fernandes R, Karuranga S, Malanda B, Cho NH. Diabetes prevalence in middle east and North Africa region (Estimates for 2017 and 2045). IDF. 2045.
[5]
Juster-Switlyk K, Smith AG. Updates in diabetic peripheral neuropathy. F1000 Res 2016; 5: F1000.
[http://dx.doi.org/10.12688/f1000research.7898.1]
[6]
Rogers LC, Frykberg RG, Armstrong DG, et al. The charcot foot in diabetes. Diabetes Care 2011; 34(9): 2123-9.
[http://dx.doi.org/10.2337/dc11-0844] [PMID: 21868781]
[7]
Alejandro EP, Taghva S, Chapman C, Bowker JH. Lower-limb amputations in patients with diabetes mellitus. Orthopedics 2011; 34(12): 885-92.
[8]
Van Schie CHM, Vermigli C, Carrington AL, Boulton A. Muscle weakness and foot deformities in diabetes: relationship to neuropathy and foot ulceration in caucasian diabetic men. Diabetes Care 2004; 27(7): 1668-73.
[http://dx.doi.org/10.2337/diacare.27.7.1668] [PMID: 15220244]
[9]
Haddad, j.Foot deformities commonly seen in diabetic patients. Identifying and understanding these difficult problems. 2002. Available from: https://www.podiatrym.com/cme/Jan02.pdf
[10]
Laclé A, Valero-juan LF. Diabetes-related lower-extremity amputation incidence and risk factors: A prospective seven-year study in Costa Rica. IRIS 2012; 32(10): 192-8.
[http://dx.doi.org/10.1590/S1020-49892012000900004]
[11]
Davies M, Burdett L, Bowling F, Ahmad N, McClennon J. The epidemiology of major lower-limb amputation in England: a systematic review highlighting methodological differences of reported trials. 22(4): 53-61.
[12]
Hoffstad O, Mitra N, Walsh J, Margolis DJ. Diabetes, lower-extremity amputation, and death. Diabetes Care 2015; 38(10): 1852-7.
[http://dx.doi.org/10.2337/dc15-0536] [PMID: 26203063]
[13]
Fortington LV, Geertzen JHB, van Netten JJ, Postema K, Rommers GM, Dijkstra PU. Short and long term mortality rates after a lower limb amputation. Eur J Vasc Endovasc Surg 2013; 46(1): 124-31.
[http://dx.doi.org/10.1016/j.ejvs.2013.03.024] [PMID: 23628328]
[14]
May K. Preventing foot ulcers. Aust Prescr 2008; 31(4): 94-6.
[http://dx.doi.org/10.18773/austprescr.2008.055]
[15]
Zhang P, Lu J, Jing Y, Tang S, Zhu D, Bi Y. Global epidemiology of diabetic foot ulceration: A systematic review and meta-analysis. Ann Med 2017; 49(2): 106-16.
[http://dx.doi.org/10.1080/07853890.2016.1231932] [PMID: 27585063]
[16]
Kruse I, Edelman S. Evaluation and treatment of diabetic foot ulcers. Clin Diabetes 2006; 24(2): 91-3.
[http://dx.doi.org/10.2337/diaclin.24.2.91]
[17]
Moore T, Shearman C. Role of screening in the prevention of diabetic foot complications: A review of the literature. Diabet Foot J 2008; 11(4)
[18]
Jambart S, Ammache Z, Haddad F, et al. Prevalence of painful diabetic peripheral neuropathy among patients with diabetes mellitus in the Middle East Region. J Int Med Res 2011; 39(2): 366-77.
[19]
Al Washali AY, Azuhairi A, Hejar AR, Amani YW. Prevalence and associated risk factors of diabetic peripheral neuropathy among diabetic patients in National Center of Diabetes in Yemen. International J Public Health Clinical Sci 2014; 1(1): 141-50.
[20]
Al-kaabi JM, Maskari F. Al, et al. Prevalence and determinants of peripheral neuropathy in patients with type 2 diabetes attending a tertiary care center in the United Arab Emirates. J Diabetes Metab 2014; 5(346): 2.
[21]
Mohamed AH, Lenjawi B. Al, Fahim Z, Hamadani A. Prevalence and correlates of diabetic peripheral neuropathy in a newly developing country: A cross-sectional study. J Diabetic Foot Complications 2016; 8(2): 31-7.
[22]
Petropoulos IN, Javed S, Azmi S, Khan A, Ponirakis G, Malik RA. Diabetic neuropathy and painful diabetic neuropathy in the Middle East and North Africa (MENA) region: Much work needs to be done. J Taibah Univ Med Sci 2016; 11(4): 284-94.
[http://dx.doi.org/10.1016/j.jtumed.2016.06.002]
[23]
Garoushi S, Johnson MI, Tashani OA. Point prevalence of painful diabetic neuropathy in the Middle East and North Africa Region: A systematic review with meta-analysis. Libyan J Medical Sci 2018; Jul 1; 2(3): 85-94.
[24]
Chahbi Z, Lahmar B, El Hadri S, et al. The prevalence of painful diabetic neuropathy in 300 Moroccan diabetics. Pan Afr Med J 2018; 31: 158.
[http://dx.doi.org/10.11604/pamj.2018.31.158.14687] [PMID: 31086614]
[25]
Garoushi S, Johnson MI, Tashani OA. A cross-sectional study to estimate the point prevalence of painful diabetic neuropathy in Eastern Libya. BMC Public Health 2019; 19: 1-7.
[http://dx.doi.org/10.1186/s12889-018-6374-9]
[26]
Abu-Shennar JA, Bayraktar NB, Bebis HB. Prevalence of peripheral neuropathic pain among adult diabetic patients (T2DM) with peripheral neuropathy and quality of life of the patients with peripheral neuropathic pain. Research Square 2020.
[27]
Alsufyani MH, Alzahrani AM, Allah AA, Abdullah RI, Alzhrani SH, Alsaab AA. Prevalence of painful diabetic peripheral neuropathy and its impact on quality of life among diabetic patients in Western region. Saudi Arabia. J Family Med Prim Care 2020; Sep; 9(9): 4897.
[28]
Bakri FG, Allan AH, Khader YS, Younes NA, Ajlouni KM. Prevalence of diabetic foot ulcer and its associated risk factors among diabetic patients in Jordan. Al-Magallat al-Tibbiyyat al-Urdunniyyat 2012; 46(2): 118-25.
[29]
Almobarak AO, Awadalla H, Osman M, Ahmed MH. Prevalence of diabetic foot ulceration and associated risk factors: An old and still major public health problem in Khartoum, Sudan? Ann Transl Med 2017; 5(17): 340.
[http://dx.doi.org/10.21037/atm.2017.07.01] [PMID: 28936434]

Rights & Permissions Print Cite
© 2024 Bentham Science Publishers | Privacy Policy