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New Emirates Medical Journal

Editor-in-Chief
ISSN (Online): 0250-6882

Research Article

Appraisal of an Innovative Surgical Approach in Treating Odontogenic Keratocyst

Author(s): Sthitaprajna Lenka, Ananya Bej*, Ramesh Nagarajappa, Swagata Sahoo, Santosh Subudhi, Karishma Rathore and Aditi Ava Rath

Volume 4, Issue 2, 2023

Published on: 18 July, 2023

Article ID: e150523216890 Pages: 6

DOI: 10.2174/0250688204666230515090459

open_access

Abstract

Objective: To estimate the recurrence of odontogenic keratocyst (OKCs) and increment of bone height upon an innovative treatment protocol of the OKC, i.e., enucleation along with the adjuvant therapy of Carnoy’s solution, followed by marsupialization.

Methods: Twenty cases of OKC treated at the Department of Oral and Maxillofacial Surgery from 2020-2021 were studied retrospectively. Clinical, radiological features and histologic features were reviewed. The patients diagnosed with OKCs were planned for enucleation with the use of Carnoy's solution and followed by marsupialization. Recurrence of the same and bone formation was analyzed concerning sites of involvement, based upon the gender and age group of patients, after undergoing the proposed treatment.

Results: Mean age of the patients was 35.15 ± 13.02, ranging from 11 to 56 years. Most (85%) patients were symptomatic, and the remaining (15%) were asymptomatic and diagnosed on a routine check-up. Males (65%) were mostly affected than females (35%). Mandible (75%) was the most frequent site of occurrence. Most lesions were diagnosed histologically as OKC on incisional biopsy. All patients were followed for six months, an increment of 11.11 ± 1.68mm bone height was seen, and none reported recurrence.

Conclusion: The steady growth of bone without any cases of recurrence was reported. Hence, clinicians can consider enucleation along with adjuvant therapy using Carnoy's solution followed by marsupialization as the treatment of choice.

Keywords: Odontogenic cysts, Enucleation, Carnoy's solution, Recurrence, Odontogenic tumors, Dental lamina.

[1]
Boffano P, Cavarra F, Agnone AM, et al. The epidemiology and management of odontogenic keratocysts (OKCs): A European multicenter study. J Craniomaxillofac Surg 2022; 50(1): 1-6.
[http://dx.doi.org/10.1016/j.jcms.2021.09.022] [PMID: 34625371]
[2]
de Castro MS, Caixeta CA, de Carli ML. Conservative surgical treatments for nonsyndromic odontogenic keratocysts: A systematic review and meta-analysis. Clin Oral Investig 2018; 22(5): 2089-101.
[http://dx.doi.org/10.1007/s00784-017-2315-8]
[3]
Brannon RB. The odontogenic keratocyst. A clinicopathologic study of 312 cases. Part II. Histologic features. Oral Surg Oral Med Oral Pathol 1977; 43(2): 233-55.
[http://dx.doi.org/10.1016/0030-4220(77)90161-X] [PMID: 264648]
[4]
Kakarantza-Angelopoulou E, Nicolatou O. Odontogenic keratocysts: Clinicopathologic study of 87 cases. J Oral Maxillofac Surg 1990; 48(6): 593-9.
[http://dx.doi.org/10.1016/S0278-2391(10)80472-0] [PMID: 2187964]
[5]
Partridge M, Towers JF. The primordial cyst (odontogenic keratocyst): Its tumour-like characteristics and behaviour. Br J Oral Maxillofac Surg 1987; 25(4): 271-9.
[http://dx.doi.org/10.1016/0266-4356(87)90065-9] [PMID: 3476151]
[6]
Crowley TE, Kaugars GE, Gunsolley JC. Odontogenic keratocysts: A clinical and histologic comparison of the parakeratin and orthokeratin variants. J Oral Maxillofac Surg 1992; 50(1): 22-6.
[http://dx.doi.org/10.1016/0278-2391(92)90187-5] [PMID: 1370082]
[7]
Lam KY, Chan AC. Odontogenic keratocysts: A clinicopathological study in Hong Kong Chinese. Laryngoscope 2000; 110(8): 1328-32.
[http://dx.doi.org/10.1097/00005537-200008000-00020] [PMID: 10942135]
[8]
Brannon RB. The odontogenic keratocyst. A clinicopathologic study of 312 cases. Part I. Clinical features. Oral Surg Oral Med Oral Pathol 1976; 42(1): 54-72.
[http://dx.doi.org/10.1016/0030-4220(76)90031-1] [PMID: 1065842]
[9]
Dammer R, Niederdellmann H, Danuner P, Nuebler-Moritz M. Conservative or radical treatment of keratocysts: A retrospective review. Br J Oral Maxillofac Surg 1997; 35(1): 46-8.
[http://dx.doi.org/10.1016/S0266-4356(97)90009-7] [PMID: 9043004]
[10]
Morgan TA, Burton CC, Qian F. A retrospective review of treatment of the odontogenic keratocyst. J Oral Maxillofac Surg 2005; 63(5): 635-9.
[http://dx.doi.org/10.1016/j.joms.2004.07.026] [PMID: 15883937]
[11]
Bande CR, Prashant MC, Sumbh B, Pandilwar PK. Prevalence, treatment and recurrence of odontogenic keratocyst in central India. J Maxillofac Oral Surg 2010; 9(2): 146-9.
[http://dx.doi.org/10.1007/s12663-010-0043-6]
[12]
Chirapathomsakul D, Sastravaha P, Jansisyanont P. A review of odontogenic keratocysts and the behavior of recurrences. Oral Surg Oral Med Oral Pathol Oral Radiol Endod 2006; 101(1): 5-9.
[http://dx.doi.org/10.1016/j.tripleo.2005.03.023] [PMID: 16360602]
[13]
Myoung H, Hong SP, Hong SD, et al. Odontogenic keratocyst: Review of 256 cases for recurrence and clinicopathologic parameters. Oral Surg Oral Med Oral Pathol Oral Radiol Endod 2001; 91(3): 328-33.
[http://dx.doi.org/10.1067/moe.2001.113109] [PMID: 11250631]
[14]
Hsun-Tau C. Odontogenic keratocyst. Oral Surg Oral Med Oral Pathol Oral Radiol Endod 1998; 86(5): 573-7.
[http://dx.doi.org/10.1016/S1079-2104(98)90348-1] [PMID: 9830650]
[15]
Donoff RB, Harper E, Guralnick WC. Collagenolytic activity in keratocysts. J Oral Surg 1972; 30(12): 879-84.
[PMID: 4343830]

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