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当代肿瘤药物靶点

Editor-in-Chief

ISSN (Print): 1568-0096
ISSN (Online): 1873-5576

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Mini-Review Article

癌症自噬分子量及其治疗意义

卷 23, 期 11, 2023

发表于: 17 May, 2023

页: [843 - 857] 页: 15

弟呕挨: 10.2174/1568009623666230412104913

价格: $65

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摘要

癌症是发展中国家妇女中一种常见的导致死亡的癌症。大多数病例是由高风险人类乳头瘤病毒（HPV16和18）的持续感染引发的。尽管有可用的治疗方法，转移、疾病复发和耐药性在癌症晚期患者中仍然很常见。因此，这种疾病需要新的前瞻性靶点。自噬被认为与宫颈癌症进展和癌症休眠有关。本文综述了自噬在宫颈癌症进展中的作用以及HPV对自噬途径的调节。此外，还讨论了靶向癌症宫颈自噬的各种治疗剂。

关键词: 自噬，宫颈癌症，人乳头瘤病毒，抗细胞凋亡，抗癌治疗，信号通路。

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