Title:Current Status of Imaging Diagnosis and Treatment of Subcentimeter
Hepatocellular Carcinoma
Volume: 3
Issue: 6
Author(s): Peng Huang, Yuyao Xiao, Changwu Zhou, Fei Wu, Chun Yang*Mengsu Zeng*
Affiliation:
- Department of Radiology, Zhongshan Hospital, Fudan University, Shanghai, China
- Department of Cancer Center,
Zhongshan Hospital, Fudan University, Shanghai, China
- Department of Radiology, Zhongshan Hospital, Fudan University, Shanghai, China
- Department of Cancer Center,
Zhongshan Hospital, Fudan University, Shanghai, China
- Department of Radiology, Shanghai Institute of Medical Imaging,
Shanghai, China
Keywords:
Hepatocellular carcinoma, subcentimeter, diagnosis, magnetic resonance imaging, disease management, early treatment.
Abstract: Significant advances in liver imaging technology have facilitated the early detection of
subcentimeter hepatocellular carcinoma (HCC). Contrast-enhanced ultrasound, computed tomography,
and magnetic resonance imaging (MRI) can be used to diagnose subcentimeter HCC
based on the typical imaging features of HCC. Ancillary imaging features such as T2 weightedimaging
mild-moderate hyperintensity, restricted diffusion, and hepatobiliary phase hypointensity
may improve the diagnostic accuracy of gadoxetic acid-enhanced MRI for subcentimeter
HCC. More information is needed to choose between immediate treatment or watchful waiting in
subcentimeter HCC. Surgical resection, ablation, and transarterial chemoembolization are effective
and safe methods for the management of subcentimeter HCC.