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Review Article

代谢组学研究人类衰老:综述

卷 24, 期 4, 2024

发表于: 15 May, 2023

页: [457 - 477] 页: 21

弟呕挨: 10.2174/1566524023666230407123727

价格: $65

摘要

在过去几年中，随着平均预期寿命的增加，世界人口正在逐渐老龄化，这带来了社会、健康和经济问题。从这个意义上说，需要更好地了解生理衰老过程成为一个迫切需要。由于对人类衰老的研究具有挑战性，细胞和动物模型被广泛用作替代方法。组学，即代谢组学，已经出现在衰老研究中，其目的是发现生物标志物，这可能有助于简化这一复杂的过程。本文旨在总结用于衰老研究的不同模型，以及它们的优点和局限性。此外，本文还收集了已发表的使用代谢组学方法发现的衰老生物标志物的文章，比较了不同研究中获得的结果。最后，描述了最常用的衰老生物标志物，以及它们在理解衰老方面的重要性。

关键词: 衰老，衰老，细胞模型，动物模型，代谢组学，衰老的生物标志物。

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