Mini-Review Article

麻醉与癌症:不仅仅是避免应激反应

卷 23, 期 4, 2023

发表于: 18 May, 2023

页: [261 - 275] 页: 15

弟呕挨: 10.2174/1566523223666230328165109

价格: $65

摘要

目前,据报道肿瘤病理的发生率不断增加。麻醉药物的影响已成为众多研究的主题。据报道,某些药物的使用可能会对预后和生存产生影响。通过研究这些药物对不同代谢途径的作用及其作用机制,我们可以更好地了解它们如何影响各种致癌标志,并确定它们对癌症进展的潜在影响。一些作用途径在肿瘤学领域广为人知,是特定治疗的靶点,例如 PI3k/AKT/mTOR、EGFR 和 Wnt/β-catenin。这篇综述通过细胞信号传导途径以及遗传、免疫和转录组学途径对麻醉药物与肿瘤细胞系之间的相互作用进行了彻底的剖析。通过这些潜在机制,旨在阐明麻醉药物选择的效果及其对肿瘤手术预后的潜在影响。

关键词: 麻醉,癌症,miRNA,丙泊酚,卤化,阿片类药物,局部麻醉剂。

图形摘要
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