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Review Article

橙皮苷治疗脑部疾病的神经保护作用:临床前循证综述

卷 24, 期 3, 2024

发表于: 18 April, 2023

页: [316 - 326] 页: 11

弟呕挨: 10.2174/1566524023666230320144722

价格: $65

摘要

神经退行性疾病(NDs)是一种进行性疾病，是世界人口老龄化中一个严重的健康问题。当代世界对传统疗法和植物药物领域的兴趣高涨，由于它们促进健康的作用和较少的副作用，被研究人员广泛接受。橙皮苷是一种存在于柑橘类水果果皮中的黄酮苷，具有多种生物活性，包括抗炎和抗氧化作用。在各种临床前研究中，橙皮苷对阿尔茨海默病、癫痫、帕金森病、多发性硬化症、抑郁症、神经性疼痛等多种脑部疾病均有显著的保护作用，并对其机制进行了研究。研究结果表明，橙皮苷的神经保护作用是通过调节抗氧化防御活性和神经生长因子，减少细胞凋亡和神经炎症途径介导的。本文综述了橙皮苷在管理和治疗多种脑部疾病中的潜在作用。

关键词: 橙皮苷，类黄酮，神经保护，癫痫，阿尔茨海默病，帕金森病。

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