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Current Respiratory Medicine Reviews

Editor-in-Chief

ISSN (Print): 1573-398X
ISSN (Online): 1875-6387

Case Report

Follow-up COVID-19 and Lung Ultrasound are Fundamental to Prove Full Recovery in Children with Interstitial Lung Disease Requiring Oxygen: A Case Report

Author(s): Marcella Contieri*, Cristiana Indolfi, Sossio Vitale, Angela Klain, Giulio Dinardo, Fabio Decimo and Michele Miraglia del Giudice

Volume 19, Issue 2, 2023

Published on: 27 March, 2023

Page: [157 - 161] Pages: 5

DOI: 10.2174/1573398X19666230314161859

Price: $65

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Abstract

Background: Children with mild or asymptomatic COVID-19 represent the majority of paediatric cases. Hospitalisation and critical care are required only in a small proportion of SARSCoV- 2 positive children who present severe symptoms, like interstitial lung disease. A quarter of children experience persistent symptoms some months later after being hospitalised, and they need to be properly followed up.

Case Presentation: The authors describe a case report of long-COVID in a 5 years old child, who was previously hospitalized for a severe case of COVID-19 (an interstitial lung disease requiring oxygen), followed up in 3 months in our Pediatric Department.

Results: After 3 months post-hospitalisation, despite his clinic history, the clinical examination was normal, during the six-minute walking test he did not desaturate, the spirometry was in the norm and the lung ultrasound did not show any pathological findings.

Conclusion: We reported a case of a child previously hospitalised for interstitial lung disease with long-COVID, who has been followed up 3 months after the hospitalisation by our Department of Pediatrics of the University ‘Luigi Vanvitelli’. Based on our experience, even in children who have experienced a severe form of COVID-19 disease and who continue to exhibit symptoms, a proper follow-up can demonstrate a full recovery in a few months.

Keywords: COVID-19, lung ultrasound, spirometry, asthma, SARS-CoV-2, chest auscultation, BMI.

Graphical Abstract
[1]
Osmanov IM, Spiridonova E, Bobkova P, et al. Risk factors for post-COVID-19 condition in previously hospitalised children using the ISARIC Global follow-up protocol: A prospective cohort study. Eur Respir J 2022; 59(2): 2101341.
[http://dx.doi.org/10.1183/13993003.01341-2021] [PMID: 34210789]
[2]
Viner RM, Ward JL, Hudson LD, et al. Systematic review of reviews of symptoms and signs of COVID-19 in children and adolescents. Arch Dis Child 2021; 106(8): 802-7.
[http://dx.doi.org/10.1136/archdischild-2020-320972] [PMID: 33334728]
[3]
Parisi GF, Brindisi G, Indolfi C, et al. Upper airway involvement in pediatric COVID-19. Pediatr Allergy Immunol 2020; 31(S26): 90-117.
[http://dx.doi.org/10.1111/pai.13356]
[4]
Parisi GF, Brindisi G, Indolfi C, et al. COVID‐19, anosmia, and ageusia in atopic children. Pediatr Allergy Immunol 2022; 33 (Suppl. 27): 99-101.
[http://dx.doi.org/10.1111/pai.13644] [PMID: 35080301]
[5]
Cui X, Zhao Z, Zhang T, et al. A systematic review and meta‐analysis of children with coronavirus disease 2019 (COVID‐19). J Med Virol 2021; 93(2): 1057-69.
[http://dx.doi.org/10.1002/jmv.26398] [PMID: 32761898]
[6]
Parcha V, Booker KS, Kalra R, et al. A retrospective cohort study of 12,306 pediatric COVID-19 patients in the United States. Sci Rep 2021; 11(1): 10231.
[http://dx.doi.org/10.1038/s41598-021-89553-1] [PMID: 33986390]
[7]
Parisi GF, Indolfi C, Decimo F, Leonardi S, Miraglia del Giudice M. COVID-19 pneumonia in children: From etiology to management. Front Pediatr 2020; 8: 616622.
[http://dx.doi.org/10.3389/fped.2020.616622] [PMID: 33381482]
[8]
Taboada M, Cariñena A, Moreno E, et al. Post-COVID-19 functional status six-months after hospitalization. J Infect 2021; 82(4): e31-3.
[http://dx.doi.org/10.1016/j.jinf.2020.12.022] [PMID: 33373650]
[9]
Raman B, Cassar MP, Tunnicliffe EM, et al. Medium-term effects of SARS-CoV-2 infection on multiple vital organs, exercise capacity, cognition, quality of life and mental health, post-hospital discharge. EClinicalMedicine 2021; 31: 100683.
[http://dx.doi.org/10.1016/j.eclinm.2020.100683] [PMID: 33490928]
[10]
Postdischarge symptoms and rehabilitation needs in survivors of COVID-19 infection: A cross-sectional evaluation. J Med Virol 2021; 93(2): 1013-22.
[11]
Götzinger F, Santiago-García B, Noguera-Julián A, et al. COVID-19 in children and adolescents in Europe: A multinational, multicentre cohort study. Lancet Child Adolesc Health 2020; 4(9): 653-61.
[http://dx.doi.org/10.1016/S2352-4642(20)30177-2] [PMID: 32593339]
[12]
Howard-Jones AR, Burgner DP, Crawford NW, et al. COVID-19 in children. II: Pathogenesis, disease spectrum and management. J Paediatr Child Health 2021; 58(1): 46-53.
[http://dx.doi.org/10.1111/jpc.15811] [PMID: 34694037]
[13]
Raveendran AV, Jayadevan R, Sashidharan S. Long COVID: An overview. Diabetes Metab Syndr 2021; 15(3): 869-75.
[http://dx.doi.org/10.1016/j.dsx.2021.04.007] [PMID: 33892403]
[14]
Parisi GF, Diaferio L, Brindisi G, et al. Cross-sectional survey on long term sequelae of pediatric COVID-19 among italian pediatricians. Children 2021; 8(9): 769.
[http://dx.doi.org/10.3390/children8090769] [PMID: 34572201]
[15]
Kikkenborg Berg S, Palm P, Nygaard U, et al. Long COVID symptoms in SARS-CoV-2-positive children aged 0-14 years and matched controls in Denmark (LongCOVIDKidsDK): A national, cross-sectional study. Lancet Child Adolesc Health 2022; 6(9): 614-23.
[16]
Yong SJ. Long COVID or post-COVID-19 syndrome: putative pathophysiology, risk factors, and treatments. Infect Dis 2021; 53(10): 737-54.
[http://dx.doi.org/10.1080/23744235.2021.1924397] [PMID: 34024217]
[17]
Manti S, Licari A. How to obtain informed consent for research. Breathe 2018; 14(2): 145-52.
[http://dx.doi.org/10.1183/20734735.001918] [PMID: 29875834]
[18]
Novembre E, Tosca M, Caffarelli C, et al. Management of BNT162b2 mRNA COVID-19 vaccine in children aged 5–11 years with allergies, asthma, and immunodeficiency: consensus of the Italian Society of Pediatric Allergy and Immunology (SIAIP). Ital J Pediatr 2022; 48(1): 76.
[http://dx.doi.org/10.1186/s13052-022-01272-z] [PMID: 35578294]
[19]
Wang D, Hu B, Hu C, et al. Clinical characteristics of 138 hospitalized patients with 2019 novel coronavirus–infected pneumonia in Wuhan, China. JAMA 2020; 323(11): 1061-9.
[http://dx.doi.org/10.1001/jama.2020.1585] [PMID: 32031570]
[20]
Pulvirenti G, Parisi GF, Giallongo A, et al. Lower airway microbiota. Front Pediatr 2019; 7: 393.
[http://dx.doi.org/10.3389/fped.2019.00393] [PMID: 31612122]
[21]
Sankar J, Dhochak N, Kabra SK, Lodha R. COVID-19 in children: Clinical approach and management. Indian J Pediatr 2020; 87(6): 433-42.
[http://dx.doi.org/10.1007/s12098-020-03292-1] [PMID: 32338347]
[22]
Zimmerman P, Curtis N. Coronavirus infections in Children Including COVID-29. Pediatr Infect Dis J 2020; 39(5): 355-68.
[23]
Irfan O, Muttalib F, Tang K, Jiang L, Lassi ZS, Bhutta Z. Clinical characteristics, treatment and outcomes of paediatric COVID-19: A systematic review and meta-analysis. Arch Dis Child 2021; 106(5): 440-8.
[http://dx.doi.org/10.1136/archdischild-2020-321385] [PMID: 33593743]
[24]
La Tessa A, Motisi MA, Marseglia GL, et al. Use of remdesivir in children with COVID-19 infection: A quick narrative review. Acta Biomed 2021; 92(S7): e2021524.
[http://dx.doi.org/10.23750/abm.v92iS7.12396] [PMID: 34842595]
[25]
Guan W, Ni Z, Hu Y, et al. Clinical characteristics of coronavirus disease 2019 in China. N Engl J Med 2020; 382(18): 1708-20.
[26]
Manti S, Licari A, Montagna L, et al. SARS-CoV-2 infection in pediatric population. Acta Biomed 2020; 91(11-S): e2020003.
[http://dx.doi.org/10.23750/abm.v91i11-S.10298] [PMID: 33004773]
[27]
Cardinale F, Ciprandi G, Barberi S, et al. Consensus statement of the Italian society of pediatric allergy and immunology for the pragmatic management of children and adolescents with allergic or immunological diseases during the COVID-19 pandemic. Ital J Pediatr 2020; 46(1): 84.
[http://dx.doi.org/10.1186/s13052-020-00843-2] [PMID: 32546234]
[28]
Zhang J, Zhou L, Yang Y, et al. Therapeutic and triage strategies for 2019 novel coronavirus disease in fever clinics. Lancet Respir Med 2019; 8(3): E11-2.
[29]
Emergency, point-of-care and clinical ultrasound guidelines in medicine. Ann Emerg Med 2017; 69(5): e27-54.
[http://dx.doi.org/10.1016/j.annemergmed.2016.08.457] [PMID: 28442101]
[30]
Pereda MA, Chavez MA, Hooper-Miele CC, et al. Lung ultrasound for the diagnosis of pneumonia in children: A meta-analysis. Pediatrics 2015; 135(4): 714-22.
[http://dx.doi.org/10.1542/peds.2014-2833] [PMID: 25780071]
[31]
Lichtenstein DA, Mezière G, Lascols N, et al. Ultrasound diagnosis of occult pneumothorax. Crit Care Med 2005; 33(6): 1231-8.
[http://dx.doi.org/10.1097/01.CCM.0000164542.86954.B4] [PMID: 15942336]
[32]
Yousefifard M, Baikpour M, Ghelichkhani P, et al. Screening performance characteristic of ultrasonography and radiography in detection of pleural effusion; a meta-analysis. Emergency 2016; 4(1): 1-10.
[PMID: 26862542]
[33]
Tierney DM, Huelster JS, Overgaard JD, et al. Comparative performance of pulmonary ultrasound, chest radiograph and CT among patients with acute respiratory failure. Crit Care Med 2020; 48(2): 151-7.
[http://dx.doi.org/10.1097/CCM.0000000000004124] [PMID: 31939782]
[34]
Tung-Chen Y. Lung ultrasound in the monitoring of COVID-19 infection. Clin Med 2020; 20(4): e62-5.
[http://dx.doi.org/10.7861/clinmed.2020-0123] [PMID: 32398268]

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