Title:Misery of Long Haulers of COVID-19 - A Review
Volume: 10
Author(s): Pragi*, Varun Kumar and Deepak Garg
Affiliation:
- Department of Pharmacy, Jagannath University, Bahadurgarh, Haryana, 124507, India
Keywords:
COVID-19, SARS-CoV-2, sequelae, long haulers, dysfunctions, post pandemic complications.
Abstract:
Background: Early in December 2019, Wuhan City, Hubei Province, China, had an epidemic
of the Coronavirus illness 2019 (COVID-19), which was brought on by a brand-new severe
acute respiratory syndrome Coronavirus 2 (SARS-CoV-2). The epidemic was deemed a Public
Health Emergency of International Concern by the World Health Organization on January 30,
2020. Many governments have implemented a range of control measures as a result of perceived
illness risk.
Objectives: The pandemic revealed that COVID-19 affects a variety of organs in addition to the
lungs, including the heart and brain, raising the risk of long-term health consequences. The illness
can affect someone's health even after recovery in a variety of ways. The long-term effects of
COVID-19 on locals are still being researched. The objective is to compile knowledge regarding
the virus and the present Post pandemic complications in Long Haulers.
Methods: We reviewed the body of publicly available literature. To discover publications published
between December 2019 and October 2020, we conducted a systematic search utilizing the
keywords in online databases such as Pub Med, Scopus, Science Direct, Up to Date, and Web of
Science. The review includes peer-reviewed original publications published that matched the qualifying
requirements.
Results: Although the majority of patients recovered quickly after receiving COVID-19, the possibility
of long-term issues induced by COVID-19 necessitates the search for and research of its late
consequences. This article aims to provide a comprehensive assessment of COVID-19 late complications
in order to determine how prevalent these symptoms are and who is most likely to be impacted.
Conclusion: There are a number of difficulties with the COVID-19 pandemic that has yet to be resolved.
Review of the literature reported several long-lasting clinical problems that affect different
phases of health, including chronic fatigue, reduced physical capacity, muscle weakness, increased
depression, anxiety, post-traumatic stress disorder and sleep problems. A complete turndown in
quality of life has been observed even one year after major Coronavirus outbreaks.
The pandemic revealed that COVID-19 affects a variety of organs in addition to the lungs, including
the heart and brain, raising the risk of long-term health consequences even after years making
them to be “Long Haulers”.
The causal agent, pathogenesis, immunological responses, epidemiology, diagnosis, therapy, and
management of the disease, as well as control and preventive efforts, are all included in this review
of the literature.