Title:Current Advances in Wound Healing and Regenerative Medicine
Volume: 19
Issue: 3
Author(s): Nesa Fani, Maryam Moradi, Roxana Zavari, Farzad Parvizpour, Adele Soltani, Zohreh Arabpour*Arefeh Jafarian*
Affiliation:
- Iranian
Tissue Bank & Research Center, Gene, Cell & Tissue Institute; Tehran University of Medical Sciences, Tehran, Iran
- Iranian
Tissue Bank & Research Center, Gene, Cell & Tissue Institute; Tehran University of Medical Sciences, Tehran, Iran
Keywords:
Chronic wounds, natural polymers, peptides, cytokines, RNA interference, gene therapy.
Abstract:
Treating chronic wounds is a common and costly challenge worldwide. More advanced treatments
are needed to improve wound healing and prevent severe complications such as infection and amputation.
Like other medical fields, there have been advances in new technologies promoting wound healing
potential.
Regenerative medicine as a new method has aroused hope in treating chronic wounds. The technology
improving wound healing includes using customizable matrices based on synthetic and natural polymers,
different types of autologous and allogeneic cells at different differentiation phases, small molecules,
peptides, and proteins as a growth factor, RNA interference, and gene therapy. In the last decade, various
types of wound dressings have been designed. Emerging dressings include a variety of interactive/
bioactive dressings and tissue-engineering skin options. However, there is still no suitable and effective
dressing to treat all chronic wounds.
This article reviews different wounds and common treatments, advanced technologies and wound dressings,
the advanced wound care market, and some interactive/bioactive wound dressings in the market.