Title:Efficacy and Biomedical Roles of Unsaturated Fatty Acids as Bioactive
Food Components
Volume: 17
Issue: 2
Author(s): Morteza Vaezi*
Affiliation:
- Department of Chemistry, Faculty of Science, Imam Khomeini International University, Qazvin, Iran
Keywords:
Unsaturated fatty acids, structure, desaturation, metabolism, biological functions, health.
Abstract: Unsaturated fatty acids (UFAs) as bioactive compounds possess a wide range of biomedical
functions and a lack or shortage of them may cause serious harm to human body health. Biochemically,
UFAs have attracted growing interest, and this attention arises not only from biomedical reasons
but also economic ones. Among these fatty acids, omega-3 and omega-6 fatty acids are considered the
most efficient and safe compounds which can be used for expanding and identification of novel functionalities.
They are considered essential membrane components and are associated with a variety of
biological processes. For example, eicosapentaenoic acid (EPA) and docosahexaenoic acid (DHA) as
polyunsaturated fatty acids (PUFAs) play a central role in the proper functioning of the nervous system
like anti-atherogenic properties and improve the functioning of the cardiovascular system. Briefly,
understanding the relationship between these properties and potential biomedical applications of
UFAs may help to elucidate and facilitate the development of novel pathogenesis strategies regarding
their disorders in human health and diseases. This review provides the most suitable functional roles
and potential mechanisms of UFAs associated with human health and nutrition.