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Current Organic Chemistry

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ISSN (Print): 1385-2728
ISSN (Online): 1875-5348

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Review Article

Chemical Composition and Bioactivities of Melia azedarach (Meliaceae): A Comprehensive Review

Author(s): Tran Trung Hieu, Nguyen Thi Chung, Vo Cong Dung and Dau Xuan Duc*

Volume 26, Issue 24, 2022

Published on: 14 February, 2023

Page: [2160 - 2187] Pages: 28

DOI: 10.2174/1385272827666230130140839

Price: $65

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Abstract

Melia azedarach L., a species of the mahogany family (Meliaceae), has long been used as a folk medicine for various diseases. Recent studies on this plant revealed that this plant contains many interesting bioactivities such as antioxidant, antimicrobial, antiviral, antifeedant, antidiabetic, antifungal, and cytotoxic activities. A diverse range of organic compounds has been isolated from this species, such as triterpenoids, limonoids, degraded limonoids, steroids, lignans, flavonoids, and phenolics. This review article will give a comprehensive overview of the chemical constituents and biological activity of Melia azedarach.

Keywords: Meliaceae, ethnopharmacology, limonoid, triterpenoid, steroid, flavonoid, insecticidal, antifungal.

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