Title:Novel 4-chloro-N-phenyl Benzamide Derivatives as p38α Mitogenactivated
Protein Kinase Inhibitors for Treating Cancer, COVID-19, and
Other Diseases
Volume: 18
Issue: 4
Author(s): Surya K. De*
Affiliation:
- Department of Chemistry, Institute of Conju-Probe, San Diego, California, USA
- Department of Chemistry, Bharath
University, Chennai, Tamil Nadu, 600126, India
Keywords:
N-Phenyl benzamide, p-38 MAPK, cancer, COVID-19, rheumatoid arthritis, inflammatory pain.
Abstract: The present disclosure relates to p38α mitogen-activated protein kinase
inhibitors, pharmaceutical compositions thereof, and the use of the p38α mitogen-activated
protein kinase inhibitors and pharmaceutical compositions thereof for treating various diseases
such as cancer, rheumatoid arthritis, amyotrophic lateral sclerosis, cystic fibrosis, cardiovascular
disease, multiple sclerosis, inflammatory bowel disease, chronic obstructive pulmonary disease
(COPD), asthma, COVID-19, acute respiratory distress syndrome (ARDS), and acute lung injury
(ALI).
