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Systematic Review Article

胃癌和循环microRNAs:最新的系统综述和诊断荟萃分析

卷 30, 期 33, 2023

发表于: 28 December, 2022

页: [3798 - 3814] 页: 17

弟呕挨: 10.2174/0929867330666221121155905

价格: $65

摘要

背景：循环microRNAs (miRNAs, miRs)现在被用作各种恶性肿瘤的无创诊断指标。 目的：我们的目的是使用荟萃分析来评估循环miRNA在胃癌中的诊断性能。 方法：在2021年10月15日之前，我们审查了数据库并有条不紊地获取了论文进行分析。随机效应荟萃分析用于构建合并诊断参数。为了发现异质性的原因，我们进行了spearman阈值效应分析和亚组分析。采用I2检验和卡方检验检验异质性。亚组分析基于样本类型(血清/血浆/血液)、归一化基因(U6、miR-16和miR-39)、qPCR母料(SYBR和Taqman)和国家进行。最后，采用Egger's漏斗图不对称检验估计发表偏倚。 结果：共纳入40篇文章，涵盖73项研究(59个microrna)，包含11022名参与者(6324例病例和4698例对照)。总体合并敏感性、特异性、阳性似然比(PLR)、阴性似然比(NLR)、诊断优势比(DOR)和曲线下面积(AUC)分别为0.75 (95% CI: 0.74-0.77)、0.79 (95% CI: 0.78-0.80)、4.081 (95% CI: 3.43-4.85)、0.28 (95% CI: 0.25-0.32)、16.08 (95% CI: 12.34-20.95)和0.877 (CI: 0.84-0.90)。我们进行了诊断价值的亚组分析，结果显示血清型、U6内参基因、SYBR母料混合物和东亚国家(中国和日本)具有更好的诊断价值。 结论：循环miRs可作为胃癌的诊断性生物标志物。然而，在胃癌的诊断，特别是早期筛查中，仍需要发现特异性的miRNA。

关键词: 胃癌，循环miRNA，诊断，生物标志物，荟萃分析，无创诊断指标。

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[1]
Talebi, A.; Borumandnia, N.; Doosti, H.; Abbasi, S.; Pourhoseingholi, M.A.; Agah, S.; Tabaeian, S.P. Development of web-based dynamic nomogram to predict survival in patients with gastric cancer: A population-based study. Sci. Rep., 2022, 12(1), 4580.
[http://dx.doi.org/10.1038/s41598-022-08465-w] [PMID: 35301382]
[2]
Kotzev, A.I.; Draganov, P.V. Carbohydrate antigen 19-9, carcinoembryonic antigen, and carbohydrate antigen 72-4 in gastric cancer: is the old band still playing? Gastrointest. Tumors, 2018, 5(1-2), 1-13.
[http://dx.doi.org/10.1159/000488240] [PMID: 30574476]
[3]
Ma, H.; He, Z.; Chen, J.; Zhang, X.; Song, P. Identifying of biomarkers associated with gastric cancer based on 11 topological analysis methods of CytoHubba. Sci. Rep., 2021, 11(1), 1331.
[http://dx.doi.org/10.1038/s41598-020-79235-9] [PMID: 33446695]
[4]
Hosseini Mojahed, F.; Aalami, A.H.; Pouresmaeil, V.; Amirabadi, A.; Qasemi Rad, M.; Sahebkar, A. Clinical evaluation of the diagnostic role of MicroRNA-155 in breast cancer. Int. J. Genomics, 2020, 2020, 9514831.
[http://dx.doi.org/10.1155/2020/9514831] [PMID: 32964011]
[5]
Aalami, A.H.; Abdeahad, H.; Shoghi, A.; Mesgari, M.; Amirabadi, A.; Sahebkar, A. Brain tumors and circulating micrornas: A systematic review and diagnostic meta-analysis. Expert Rev. Mol. Diagn., 2022, 22(2), 201-211.
[http://dx.doi.org/10.1080/14737159.2022.2019016] [PMID: 34906021]
[6]
Liu, X.; Ma, R.; Yi, B.; Riker, A.I.; Xi, Y. MicroRNAs are involved in the development and progression of gastric cancer. Acta Pharmacol. Sin., 2021, 42(7), 1018-1026.
[http://dx.doi.org/10.1038/s41401-020-00540-0] [PMID: 33037405]
[7]
Qasemi Rad, M.; Pouresmaeil, V.; Hosseini Mojahed, F.; Amirabadi, A.; Aalami, A.H. Clinicopathological utility of miR-203a-3p in diagnosing colorectal cancer. Mol. Biol. Rep., 2022, 49(7), 6975-6985.
[http://dx.doi.org/10.1007/s11033-022-07465-3] [PMID: 35511316]
[8]
Oliveira, A.; Castanhole-Nunes, M.; Biselli-Chicote, P.; Pavarino, É.; Silva, R.; Silva, R.; Goloni-Bertollo, E.M. Differential expression of angiogenesis-related miRNAs and VEGFA in cirrhosis and hepatocellular carcinoma. Arch. Med. Sci., 2020, 16(5), 1150-1157.
[http://dx.doi.org/10.5114/aoms.2020.97967] [PMID: 32864004]
[9]
Huang, F.; Tang, W.; Lei, Y. MicroRNA-107 promotes apoptosis of acute myelocytic leukemia cells by targeting RAD51. Arch. Med. Sci., 2021, 17(4), 1044-1055.
[http://dx.doi.org/10.5114/aoms.2020.92860] [PMID: 34336032]
[10]
Pu, R.; Pu, M.; Huang, H.; Cui, Y. MicroRNA 144 inhibits cell migration and invasion and regulates inflammatory cytokine secretion through targeting toll like receptor 2 in non-small cell lung cancer. Arch. Med. Sci., 2021, 17(4), 1028-1037.
[http://dx.doi.org/10.5114/aoms.2020.93084] [PMID: 34336030]
[11]
Wang, H.; Liu, G.; Li, T.; Wang, N.; Wu, J.; Zhi, H. MiR-330-3p functions as a tumor suppressor that regulates glioma cell proliferation and migration by targeting CELF1. Arch. Med. Sci., 2020, 16(5), 1166-1175.
[http://dx.doi.org/10.5114/aoms.2020.95027] [PMID: 32864006]
[12]
Zhang, H.; Bao, J.; Zhao, S.; Huo, Z.; Li, B. MicroRNA-490-3p suppresses hepatocellular carcinoma cell proliferation and migration by targeting the aurora kinase A gene (AURKA). Arch. Med. Sci., 2020, 16(2), 395-406.
[http://dx.doi.org/10.5114/aoms.2019.91351] [PMID: 32190151]
[13]
Zhao, M.; Wang, K.; Shang, J.; Liang, Z.; Zheng, W.; Gu, J. MiR-345-5p inhibits tumorigenesis of papillary thyroid carcinoma by targeting SETD7. Arch. Med. Sci., 2020, 16(4), 888-897.
[http://dx.doi.org/10.5114/aoms.2019.83823] [PMID: 32542092]
[14]
Zhihong, Z.; Rubin, C.; Liping, L.; Anpeng, M.; Hui, G.; Yanting, W.; Zhenxiu, S. MicroRNA-1179 regulates proliferation and chemosensitivity of human ovarian cancer cells by targeting the PTEN-mediated PI3K/AKT signaling pathway. Arch. Med. Sci., 2020, 16(4), 907-914.
[http://dx.doi.org/10.5114/aoms.2019.86798] [PMID: 32542094]
[15]
Salarinia, R.; Sahebkar, A.; Peyvandi, M.; Reza Mirzaei, H.; Reza Jaafari, M.; Matbou Riahi, M.; Ebrahimnejad, H.; Sadri Nahand, J.; Hadjati, J.; Ostadi Asrami, M.; Fadaei, S.; Salehi, R.; Mirzaei, H. Epi-drugs and epi-mirs: Moving beyond current cancer therapies. Curr. Cancer Drug Targets, 2016, 16(9), 773-788.
[http://dx.doi.org/10.2174/1568009616666151207110143] [PMID: 26638884]
[16]
Azarbarzin, S.; Safaralizadeh, R.; Khojasteh, M.B.; Baghbanzadeh, A.; Baradaran, B. Current perspectives on the dysregulated microRNAs in gastric cancer. Mol. Biol. Rep., 2020, 47(9), 7253-7264.
[http://dx.doi.org/10.1007/s11033-020-05720-z] [PMID: 32776162]
[17]
Chang, J.; Liu, S.; Li, B.; Huo, Z.; Wang, X.; Zhang, H. MiR-338-3p improved lung adenocarcinoma by AKAP12 suppression. Arch. Med. Sci., 2021, 17(2), 462-473.
[http://dx.doi.org/10.5114/aoms.2019.90913] [PMID: 33747281]
[18]
Chen, Z.; Gao, Y.; Gao, S.; Song, D.; Feng, Y. MiR-135b-5p promotes viability, proliferation, migration and invasion of gastric cancer cells by targeting Krüppel-like factor 4 (KLF4). Arch. Med. Sci., 2020, 16(1), 167-176.
[http://dx.doi.org/10.5114/aoms.2019.87761] [PMID: 32051721]
[19]
Krupa, R.; Malecki, W.; Czarny, P.; Strycharz, J.; Jablkowski, M.; Kordek, R.; Szemraj, J.; Sliwinski, T. MicroRNA profile and iron-related gene expression in hepatitis C-related hepatocellular carcinoma: A preliminary study. Arch. Med. Sci., 2021, 17(5), 1175-1183.
[http://dx.doi.org/10.5114/aoms.2019.86613] [PMID: 34522246]
[20]
Li, H.; Liu, D.; Liu, L.; Huang, S.; Ma, A.; Zhang, X. The role of HOTAIR/miR-152-3p/LIN28B in regulating the progression of endometrial squamous carcinoma. Arch. Med. Sci., 2021, 17(2), 434-448.
[http://dx.doi.org/10.5114/aoms.2019.89632] [PMID: 33747279]
[21]
Aalami, A.H.; Abdeahad, H.; Mesgari, M.; Sahebkar, A. MicroRNA-223 in gastrointestinal cancers: A systematic review and diagnostic meta-analysis. Eur. J. Clin. Invest., 2021, 51(2), e13448.
[http://dx.doi.org/10.1111/eci.13448] [PMID: 33244751]
[22]
Aalami, A.H.; Abdeahad, H.; Mesgari, M. Circulating miR-21 as a potential biomarker in human digestive system carcinoma: A systematic review and diagnostic meta- analysis. Biomarkers, 2021, 26(2), 103-113.
[http://dx.doi.org/10.1080/1354750X.2021.1875504] [PMID: 33434077]
[23]
Fattahi, S.; Nikbakhsh, N.; Ranaei, M.; Sabour, D.; Akhavan-Niaki, H. Association of sonic hedgehog signaling pathway genes IHH, BOC, RAB23a and MIR195-5p, MIR509-3-5p, MIR6738-3p with gastric cancer stage. Sci. Rep., 2021, 11(1), 1-12.
[PMID: 33414495]
[24]
Ahadi, A. Dysregulation of miRNAs as a signature for diagnosis and prognosis of gastric cancer and their involvement in the mechanism underlying gastric carcinogenesis and progression. IUBMB Life, 2020, 72(5), 884-898.
[http://dx.doi.org/10.1002/iub.2259] [PMID: 32078236]
[25]
Ghafouri-Fard, S.; Vafaee, R.; Shoorei, H.; Taheri, M. MicroRNAs in gastric cancer: Biomarkers and therapeutic targets. Gene, 2020, 757, 144937.
[http://dx.doi.org/10.1016/j.gene.2020.144937] [PMID: 32640300]
[26]
Kipkeeva, F.; Muzaffarova, T.; Korotaeva, A.; Nikulin, M.; Grishina, K.; Mansorunov, D.; Apanovich, P.; Karpukhin, A. MicroRNA in gastric cancer development: Mechanisms and biomarkers. Diagnostics, 2020, 10(11), 891.
[http://dx.doi.org/10.3390/diagnostics10110891] [PMID: 33142817]
[27]
Fathullahzadeh, S.; Mirzaei, H.; Honardoost, M.A.; Sahebkar, A.; Salehi, M. Circulating microRNA-192 as a diagnostic biomarker in human chronic lymphocytic leukemia. Cancer Gene Ther., 2016, 23(10), 327-332.
[http://dx.doi.org/10.1038/cgt.2016.34] [PMID: 27659777]
[28]
Ghandadi, M.; Sahebkar, A. MicroRNA-34a and its target genes: Key factors in cancer multidrug resistance. Curr. Pharm. Des., 2016, 22(7), 933-939.
[http://dx.doi.org/10.2174/1381612822666151209153729] [PMID: 26648462]
[29]
Kim, Y.J.; Jeong, S.; Jung, W.Y.; Choi, J.W.; Hwang, K.C.; Kim, S.W.; Lee, Y.C. miRNAs as potential biomarkers for the progression of gastric cancer inhibit CREBZF and regulate migration of gastric adenocarcinoma cells. Int. J. Med. Sci., 2020, 17(6), 693-701.
[http://dx.doi.org/10.7150/ijms.42654] [PMID: 32218690]
[30]
Zhou, L.; Lu, Y.; Liu, J.; Long, S.; Liu, H.; Zhang, J.; Zhang, T. The role of miR-21/RECK in the inhibition of osteosarcoma by curcumin. Mol. Cell. Probes, 2020, 51, 101534.
[http://dx.doi.org/10.1016/j.mcp.2020.101534] [PMID: 32081769]
[31]
Li, J.; Wei, H.; Liu, Y.; Li, Q.; Guo, H.; Guo, Y.; Chang, Z. Curcumin inhibits hepatocellular carcinoma via regulating miR-21/TIMP3 Axis. Evid. Based Complement. Alternat. Med., 2020, 2020, 2892917.
[http://dx.doi.org/10.1155/2020/2892917] [PMID: 32724322]
[32]
Shen, Z.; Xu, X.; Lv, L.; Dai, H.; Chen, J.; Chen, B. miR-21 overexpression promotes esophageal squamous cell carcinoma invasion and migration by repressing tropomyosin 1. Gastroenterol. Res. Pract., 2020, 2020, 6478653.
[http://dx.doi.org/10.1155/2020/6478653] [PMID: 33193757]
[33]
Kangas, R.; Pöllänen, E.; Rippo, M.R.; Lanzarini, C.; Prattichizzo, F.; Niskala, P.; Jylhävä, J.; Sipilä, S.; Kaprio, J.; Procopio, A.D.; Capri, M.; Franceschi, C.; Olivieri, F.; Kovanen, V. Circulating miR-21, miR-146a and Fas ligand respond to postmenopausal estrogen-based hormone replacement therapy - A study with monozygotic twin pairs. Mech. Ageing Dev., 2014, 143-144, 1-8.
[http://dx.doi.org/10.1016/j.mad.2014.11.001] [PMID: 25448133]
[34]
Huang, S.X.; Fan, W.Y.; Wang, L.; Liu, H.; Wang, X.; Zhao, H.; Jiang, W.B. Maspin inhibits MCF‑7 cell invasion and proliferation by downregulating miR‑21 and increasing the expression of its target genes. Oncol. Lett., 2020, 19(4), 2621-2628.
[http://dx.doi.org/10.3892/ol.2020.11360] [PMID: 32218812]
[35]
Zhao, M.; Zhu, N.; Hao, F.; Song, Y.; Wang, Z.; Ni, Y.; Ding, L. The regulatory role of noncoding RNAs on programmed cell death 4 in inflammation and cancer. Front. Oncol., 2019, 9, 919.
[http://dx.doi.org/10.3389/fonc.2019.00919] [PMID: 31620370]
[36]
Chen, D.; Guo, Y.; Chen, Y.; Guo, Q.; Chen, J.; Li, Y.; Zheng, Q.; Jiang, M.; Xi, M.; Cheng, L. LncRNA growth arrest-specific transcript 5 targets miR-21 gene and regulates bladder cancer cell proliferation and apoptosis through PTEN. Cancer Med., 2020, 9(8), 2846-2858.
[http://dx.doi.org/10.1002/cam4.2664] [PMID: 32069387]
[37]
Zhuang, H.; Wang, H.; Yang, H.; Li, H. Exosome-encapsulated MicroRNA-21 from esophageal squamous cell carcinoma cells enhances angiogenesis of human umbilical venous endothelial cells by targeting SPRY1. Cancer Manag. Res., 2020, 12, 10651-10667.
[http://dx.doi.org/10.2147/CMAR.S259077] [PMID: 33149673]
[38]
Mohammadlou, M.; Abdollahi, M.; Hemati, M. Apoptotic effect of berberine via Bcl-2, ROR1, and mir-21 in patients with B-chronic lymphocytic leukemia. Phytother. Res., 2020, 35(4), 2025-2033.
[PMID: 33174291]
[39]
Nedaeinia, R.; Sharifi, M.; Avan, A.; Kazemi, M.; Rafiee, L.; Ghayour-Mobarhan, M.; Salehi, R. Locked nucleic acid anti-miR-21 inhibits cell growth and invasive behaviors of a colorectal adenocarcinoma cell line: LNA-anti-miR as a novel approach. Cancer Gene Ther., 2016, 23(8), 246-253.
[http://dx.doi.org/10.1038/cgt.2016.25] [PMID: 27364574]
[40]
Papagiannakopoulos, T.; Shapiro, A.; Kosik, K.S. MicroRNA-21 targets a network of key tumor-suppressive pathways in glioblastoma cells. Cancer Res., 2008, 68(19), 8164-8172.
[http://dx.doi.org/10.1158/0008-5472.CAN-08-1305] [PMID: 18829576]
[41]
Abe, S.; Matsuzaki, J.; Sudo, K.; Oda, I.; Katai, H.; Kato, K.; Takizawa, S.; Sakamoto, H.; Takeshita, F.; Niida, S.; Saito, Y.; Ochiya, T. A novel combination of serum microRNAs for the detection of early gastric cancer. Gastric Cancer, 2021, 24(4), 835-843.
[http://dx.doi.org/10.1007/s10120-021-01161-0] [PMID: 33743111]
[42]
Ahadi, A. A systematic review of microRNAs as potential biomarkers for diagnosis and prognosis of gastric cancer. Immunogenetics, 2021, 73(2), 155-161.
[http://dx.doi.org/10.1007/s00251-020-01201-6] [PMID: 33399935]
[43]
Page, M.J.; McKenzie, J.E.; Bossuyt, P.M.; Boutron, I.; Hoffmann, T.C.; Mulrow, C.D.; Shamseer, L.; Tetzlaff, J.M.; Moher, D. Updating guidance for reporting systematic reviews: Development of the PRISMA 2020 statement. J. Clin. Epidemiol., 2021, 134, 103-112.
[http://dx.doi.org/10.1016/j.jclinepi.2021.02.003] [PMID: 33577987]
[44]
Moher, D.; Shamseer, L.; Clarke, M.; Ghersi, D.; Liberati, A.; Petticrew, M.; Shekelle, P.; Stewart, L.A. Preferred reporting items for systematic review and meta-analysis protocols (PRISMA-P) 2015 statement. Syst. Rev., 2015, 4(1), 1.
[http://dx.doi.org/10.1186/2046-4053-4-1] [PMID: 25554246]
[45]
Moses, L.E.; Shapiro, D.; Littenberg, B. Combining independent studies of a diagnostic test into a summary roc curve: Data-analytic approaches and some additional considerations. Stat. Med., 1993, 12(14), 1293-1316.
[http://dx.doi.org/10.1002/sim.4780121403] [PMID: 8210827]
[46]
Furuya-Kanamori, L.; Kostoulas, P.; Doi, S.A.R. A new method for synthesizing test accuracy data outperformed the bivariate method. J. Clin. Epidemiol., 2021, 132, 51-58.
[http://dx.doi.org/10.1016/j.jclinepi.2020.12.015] [PMID: 33333166]
[47]
Higgins, J.P.T.; Thompson, S.G.; Deeks, J.J.; Altman, D.G. Measuring inconsistency in meta-analyses. BMJ, 2003, 327(7414), 557-560.
[http://dx.doi.org/10.1136/bmj.327.7414.557] [PMID: 12958120]
[48]
Liu, X.; Cai, H.; Wang, Y. Prognostic significance of tumour markers in Chinese patients with gastric cancer. ANZ J. Surg., 2014, 84(6), 448-453.
[http://dx.doi.org/10.1111/j.1445-2197.2012.06287.x] [PMID: 23013163]
[49]
Zhu, H.; Wu, H.; Liu, X.; Evans, B.R.; Medina, D.J.; Liu, C.G.; Yang, J.M. Role of MicroRNA miR-27a and miR-451 in the regulation of MDR1/P-glycoprotein expression in human cancer cells. Biochem. Pharmacol., 2008, 76(5), 582-588.
[http://dx.doi.org/10.1016/j.bcp.2008.06.007] [PMID: 18619946]
[50]
Liu, F.; Bu, Z.; Zhao, F.; Xiao, D. Increased T-helper 17 cell differentiation mediated by exosome-mediated microRNA-451 redistribution in gastric cancer infiltrated T cells. Cancer Sci., 2018, 109(1), 65-73.
[http://dx.doi.org/10.1111/cas.13429] [PMID: 29059496]
[51]
Wang, Q.X.; Zhu, Y.Q.; Zhang, H.; Xiao, J. Altered MiRNA expression in gastric cancer: A systematic review and meta-analysis. Cell. Physiol. Biochem., 2015, 35(3), 933-944.
[http://dx.doi.org/10.1159/000369750] [PMID: 25633747]
[52]
Zhang, B.G.; Li, J.F.; Yu, B.Q.; Zhu, Z.G.; Liu, B.Y.; Yan, M. microRNA-21 promotes tumor proliferation and invasion in gastric cancer by targeting PTEN. Oncol. Rep., 2012, 27(4), 1019-1026.
[http://dx.doi.org/10.3892/or.2012.1645] [PMID: 22267008]
[53]
Yamanaka, S.; Olaru, A.V.; An, F.; Luvsanjav, D.; Jin, Z.; Agarwal, R.; Tomuleasa, C.; Popescu, I.; Alexandrescu, S.; Dima, S.; Chivu-Economescu, M.; Montgomery, E.A.; Torbenson, M.; Meltzer, S.J.; Selaru, F.M. MicroRNA-21 inhibits Serpini1, a gene with novel tumour suppressive effects in gastric cancer. Dig. Liver Dis., 2012, 44(7), 589-596.
[http://dx.doi.org/10.1016/j.dld.2012.02.016] [PMID: 22464652]
[54]
Zhu, X.; Lv, M.; Wang, H.; Guan, W. Identification of circulating microRNAs as novel potential biomarkers for gastric cancer detection: A systematic review and meta-analysis. Dig. Dis. Sci., 2014, 59(5), 911-919.
[http://dx.doi.org/10.1007/s10620-013-2970-9] [PMID: 24337687]
[55]
Larner, A.J. The Q* index: A useful global measure of dementia screening test accuracy. Dement. Geriatr. Cogn. Disord. Extra, 2015, 5(2), 265-270.
[http://dx.doi.org/10.1159/000430784] [PMID: 26195982]
[56]
Naredo, E.; Uson, J.; Jiménez-Palop, M.; Martínez, A.; Vicente, E.; Brito, E.; Rodríguez, A.; Cornejo, F.J.; Castañeda, S.; Martínez, M.J.; Sanz, J.; Möller, I.; Batlle-Gualda, E.; Garrido, J.; Pascual, E. Ultrasound-detected musculoskeletal urate crystal deposition: Which joints and what findings should be assessed for diagnosing gout? Ann. Rheum. Dis., 2014, 73(8), 1522-1528.
[http://dx.doi.org/10.1136/annrheumdis-2013-203487] [PMID: 23709244]
[57]
Li, B; Zhao, Y; Guo, G Plasma microRNAs, miR-223, miR-21 and miR-218, as novel potential biomarkers for gastric cancer detection. PLoS One, 2012, 7(7), e41629.
[http://dx.doi.org/10.1371/journal.pone.0041629]
[58]
Tsujiura, M.; Komatsu, S.; Ichikawa, D.; Shiozaki, A.; Konishi, H.; Takeshita, H.; Moriumura, R.; Nagata, H.; Kawaguchi, T.; Hirajima, S.; Arita, T.; Fujiwara, H.; Okamoto, K.; Otsuji, E. Circulating miR-18a in plasma contributes to cancer detection and monitoring in patients with gastric cancer. Gastric Cancer, 2015, 18(2), 271-279.
[http://dx.doi.org/10.1007/s10120-014-0363-1] [PMID: 24626859]
[59]
Kong, Y.; Ning, L.; Qiu, F.; Yu, Q.; Cao, B. Clinical significance of serum miR-25 as a diagnostic and prognostic biomarker in human gastric cancer. Cancer Biomark., 2019, 24(4), 477-483.
[http://dx.doi.org/10.3233/CBM-182213] [PMID: 30909187]
[60]
Wang, H.; Wang, L.; Wu, Z.; Sun, R.; Jin, H.; Ma, J.; Liu, L.; Ling, R.; Yi, J.; Wang, L.; Bian, J.; Chen, J.; Li, N.; Yuan, S.; Yun, J. Three dysregulated microRNAs in serum as novel biomarkers for gastric cancer screening. Med. Oncol., 2014, 31(12), 298.
[http://dx.doi.org/10.1007/s12032-014-0298-8] [PMID: 25367852]
[61]
Juzėnas, S.; Saltenienė, V.; Kupcinskas, J.; Link, A.; Kiudelis, G.; Jonaitis, L.; Jarmalaite, S.; Kupcinskas, L.; Malfertheiner, P.; Skieceviciene, J. Analysis of deregulated microRNAs and their target genes in gastric cancer. PLoS One, 2015, 10(7), e0132327.
[http://dx.doi.org/10.1371/journal.pone.0132327] [PMID: 26172537]
[62]
Aalami, AH; Pouresmaeil, V; Amirabadi, A; Mojahed, FH; Rad, MQ; Sahebkar, A Evaluation of the diagnostic properties of serum hsa-miR-223-5p in the detection of gastric cancer: A case-control study. Anti-Cancer Agents Med. Chem., 2020, 20(7), 800-808.
[63]
Wu, J.; Li, G.; Yao, Y.; Wang, Z.; Sun, W.; Wang, J. MicroRNA-421 is a new potential diagnosis biomarker with higher sensitivity and specificity than carcinoembryonic antigen and cancer antigen 125 in gastric cancer. Biomarkers, 2015, 20(1), 58-63.
[http://dx.doi.org/10.3109/1354750X.2014.992812] [PMID: 25510566]
[64]
Zhao, G.; Jiang, T.; Liu, Y.; Huai, G.; Lan, C.; Li, G.; Jia, G.; Wang, K.; Yang, M. Droplet digital PCR-based circulating microRNA detection serve as a promising diagnostic method for gastric cancer. BMC Cancer, 2018, 18(1), 676.
[http://dx.doi.org/10.1186/s12885-018-4601-5] [PMID: 29929476]
[65]
Valladares-Ayerbes, M.; Reboredo, M.; Medina-Villaamil, V.; Iglesias-Díaz, P.; Lorenzo-Patiño, M.J.; Haz, M.; Santamarina, I.; Blanco, M.; Fernández-Tajes, J.; Quindós, M.; Carral, A.; Figueroa, A.; Antón-Aparicio, L.M.; Calvo, L. Circulating miR-200c as a diagnostic and prognostic biomarker for gastric cancer. J. Transl. Med., 2012, 10(1), 186.
[http://dx.doi.org/10.1186/1479-5876-10-186] [PMID: 22954417]
[66]
Zhou, H.; Guo, J.M.; Lou, Y.R.; Zhang, X.J.; Zhong, F.D.; Jiang, Z.; Cheng, J.; Xiao, B.X. Detection of circulating tumor cells in peripheral blood from patients with gastric cancer using microRNA as a marker. J. Mol. Med., 2010, 88(7), 709-717.
[http://dx.doi.org/10.1007/s00109-010-0617-2] [PMID: 20349219]
[67]
Liu, X.; Kwong, A.; Sihoe, A.; Chu, K.M. Plasma miR-940 may serve as a novel biomarker for gastric cancer. Tumour Biol., 2016, 37(3), 3589-3597.
[http://dx.doi.org/10.1007/s13277-015-4019-5] [PMID: 26456959]
[68]
Emami, S.S.; Nekouian, R.; Akbari, A.; Faraji, A.; Abbasi, V.; Agah, S. Evaluation of circulating miR-21 and miR-222 as diagnostic biomarkers for gastric cancer. J. Cancer Res. Ther., 2019, 15(1), 115-119.
[PMID: 30880765]
[69]
Li, Y.; Sun, H.; Guan, J.; Ji, T.; Wang, X. Serum microRNA-381: A potential marker for early diagnosis of gastric cancer. Yonsei Med. J., 2019, 60(8), 720-726.
[http://dx.doi.org/10.3349/ymj.2019.60.8.720] [PMID: 31347326]
[70]
Shi, Y.; Wang, Z.; Zhu, X.; Chen, L.; Ma, Y.; Wang, J.; Yang, X.; Liu, Z. Exosomal miR-1246 in serum as a potential biomarker for early diagnosis of gastric cancer. Int. J. Clin. Oncol., 2020, 25(1), 89-99.
[http://dx.doi.org/10.1007/s10147-019-01532-9] [PMID: 31506750]
[71]
Tsujiura, M.; Ichikawa, D.; Komatsu, S.; Shiozaki, A.; Takeshita, H.; Kosuga, T.; Konishi, H.; Morimura, R.; Deguchi, K.; Fujiwara, H.; Okamoto, K.; Otsuji, E. Circulating microRNAs in plasma of patients with gastric cancers. Br. J. Cancer, 2010, 102(7), 1174-1179.
[http://dx.doi.org/10.1038/sj.bjc.6605608] [PMID: 20234369]
[72]
Qiu, X.; Zhang, J.; Shi, W.; Liu, S.; Kang, M.; Chu, H.; Wu, D.; Tong, N.; Gong, W.; Tao, G.; Zhao, Q.; Qiang, F.; Zhu, H.; Wu, Q.; Wang, M.; Zhang, Z. Circulating microRNA-26a in plasma and its potential diagnostic value in gastric cancer. PLoS One, 2016, 11(3), e0151345.
[http://dx.doi.org/10.1371/journal.pone.0151345] [PMID: 27010210]
[73]
Zhu, C.; Ren, C.; Han, J.; Ding, Y.; Du, J.; Dai, N.; Dai, J.; Ma, H.; Hu, Z.; Shen, H.; Xu, Y.; Jin, G. A five-microRNA panel in plasma was identified as potential biomarker for early detection of gastric cancer. Br. J. Cancer, 2014, 110(9), 2291-2299.
[http://dx.doi.org/10.1038/bjc.2014.119] [PMID: 24595006]
[74]
Zhang, J.; Song, Y.; Zhang, C.; Zhi, X.; Fu, H.; Ma, Y.; Chen, Y.; Pan, F.; Wang, K.; Ni, J.; Jin, W.; He, X.; Su, H.; Cui, D. Circulating MiR-16-5p and MiR-19b-3p as two novel potential biomarkers to indicate progression of gastric cancer. Theranostics, 2015, 5(7), 733-745.
[http://dx.doi.org/10.7150/thno.10305] [PMID: 25897338]
[75]
Konishi, H.; Ichikawa, D.; Komatsu, S.; Shiozaki, A.; Tsujiura, M.; Takeshita, H.; Morimura, R.; Nagata, H.; Arita, T.; Kawaguchi, T.; Hirashima, S.; Fujiwara, H.; Okamoto, K.; Otsuji, E. Detection of gastric cancer-associated microRNAs on microRNA microarray comparing pre- and post-operative plasma. Br. J. Cancer, 2012, 106(4), 740-747.
[http://dx.doi.org/10.1038/bjc.2011.588] [PMID: 22262318]
[76]
Li, C.; Li, J.F.; Cai, Q.; Qiu, Q.Q.; Yan, M.; Liu, B.Y.; Zhu, Z.G. miRNA-199a-3p in plasma as a potential diagnostic biomarker for gastric cancer. Ann. Surg. Oncol., 2013, 20(Suppl. 3), 397-405.
[http://dx.doi.org/10.1245/s10434-012-2600-3] [PMID: 22956063]
[77]
Song, M.; Pan, K.; Su, H.; Zhang, L.; Ma, J.; Li, J.; Yuasa, Y.; Kang, D.; Kim, Y.S.; You, W. Identification of serum microRNAs as novel non-invasive biomarkers for early detection of gastric cancer. PLoS One, 2012, 7(3), e33608.
[http://dx.doi.org/10.1371/journal.pone.0033608] [PMID: 22432036]
[78]
Huang, S.; Wang, J.; Li, J.; Luo, Q.; Zhao, M.; Zheng, L.; Dong, X.; Chen, C.; Che, Y.; Liu, P.; Qi, J.; Huang, C. Serum microRNA expression profile as a diagnostic panel for gastric cancer. Jpn. J. Clin. Oncol., 2016, 46(9), 811-818.
[http://dx.doi.org/10.1093/jjco/hyw085] [PMID: 27380811]
[79]
Liu, R.; Zhang, C.; Hu, Z.; Li, G.; Wang, C.; Yang, C.; Huang, D.; Chen, X.; Zhang, H.; Zhuang, R.; Deng, T.; Liu, H.; Yin, J.; Wang, S.; Zen, K.; Ba, Y.; Zhang, C.Y. A five-microRNA signature identified from genome-wide serum microRNA expression profiling serves as a fingerprint for gastric cancer diagnosis. Eur. J. Cancer, 2011, 47(5), 784-791.
[http://dx.doi.org/10.1016/j.ejca.2010.10.025] [PMID: 21112772]
[80]
Wang, N.; Wang, L.; Yang, Y.; Gong, L.; Xiao, B.; Liu, X. A serum exosomal microRNA panel as a potential biomarker test for gastric cancer. Biochem. Biophys. Res. Commun., 2017, 493(3), 1322-1328.
[http://dx.doi.org/10.1016/j.bbrc.2017.10.003] [PMID: 28986250]
[81]
Zeng, Q.; Jin, C.; Chen, W.; Xia, F.; Wang, Q.; Fan, F.; Du, J.; Guo, Y.; Lin, C.; Yang, K.; Li, J.; Peng, X.; Li, X.; Cao, K. Downregulation of serum miR-17 and miR-106b levels in gastric cancer and benign gastric diseases. Chin. J. Cancer Res., 2014, 26(6), 711-716.
[PMID: 25561770]
[82]
Li, F.; Guo, Y.; Liu, J.; Zhang, R. The significance of elevated plasma expression of microRNA 106b~25 clusters in gastric cancer. PLoS One, 2017, 12(5), e0178427.
[http://dx.doi.org/10.1371/journal.pone.0178427] [PMID: 28562634]
[83]
Chen, S.; Zhu, J.; Yu, F.; Tian, Y.; Ma, S.; Liu, X. Combination of miRNA and RNA functions as potential biomarkers for gastric cancer. Tumour Biol., 2015, 36(12), 9909-9918.
[http://dx.doi.org/10.1007/s13277-015-3756-9] [PMID: 26168960]
[84]
Jiang, X.; Wang, W.; Yang, Y.; Du, L.; Yang, X.; Wang, L.; Zheng, G.; Duan, W.; Wang, R.; Zhang, X.; Wang, L.; Chen, X.; Wang, C. Identification of circulating microRNA signatures as potential noninvasive biomarkers for prediction and prognosis of lymph node metastasis in gastric cancer. Oncotarget, 2017, 8(39), 65132-65142.
[http://dx.doi.org/10.18632/oncotarget.17789] [PMID: 29029418]
[85]
Liu, S.; Suo, J.; Wang, C.; Sun, X.; Wang, D.; He, L.; Zhang, Y.; Li, W. Prognostic significance of low miR-144 expression in gastric cancer. Cancer Biomark., 2017, 20(4), 547-552.
[http://dx.doi.org/10.3233/CBM-170351] [PMID: 28800316]
[86]
Liu, H.; Zhu, L.; Liu, B.; Yang, L.; Meng, X.; Zhang, W.; Ma, Y.; Xiao, H. Genome-wide microRNA profiles identify miR-378 as a serum biomarker for early detection of gastric cancer. Cancer Lett., 2012, 316(2), 196-203.
[http://dx.doi.org/10.1016/j.canlet.2011.10.034] [PMID: 22169097]
[87]
Tsai, M.M.; Wang, C.S.; Tsai, C.Y.; Huang, C.G.; Lee, K.F.; Huang, H.W.; Lin, Y.H.; Chi, H.C.; Kuo, L.M.; Lu, P.H.; Lin, K.H. Circulating microRNA-196a/b are novel biomarkers associated with metastatic gastric cancer. Eur. J. Cancer, 2016, 64, 137-148.
[http://dx.doi.org/10.1016/j.ejca.2016.05.007] [PMID: 27420607]
[88]
Hou, C.G.; Luo, X.Y.; Li, G. Diagnostic and prognostic value of serum microRNA-206 in patients with gastric cancer. Cell. Physiol. Biochem., 2016, 39(4), 1512-1520.
[http://dx.doi.org/10.1159/000447854] [PMID: 27614739]
[89]
Zheng, Y.; Cui, L.; Sun, W.; Zhou, H.; Yuan, X.; Huo, M.; Chen, J.; Lou, Y.; Guo, J. MicroRNA-21 is a new marker of circulating tumor cells in gastric cancer patients. Cancer Biomark., 2012, 10(2), 71-77.
[http://dx.doi.org/10.3233/CBM-2011-0231] [PMID: 22430134]
[90]
Wang, B.; Zhang, Q. The expression and clinical significance of circulating microRNA-21 in serum of five solid tumors. J. Cancer Res. Clin. Oncol., 2012, 138(10), 1659-1666.
[http://dx.doi.org/10.1007/s00432-012-1244-9] [PMID: 22638884]
[91]
Wu, J.; Li, G.; Wang, Z.; Yao, Y.; Chen, R.; Pu, X.; Wang, J. Circulating microRNA-21 is a potential diagnostic biomarker in gastric cancer. Dis. Markers, 2015, 2015, 435656.
[http://dx.doi.org/10.1155/2015/435656] [PMID: 26063956]
[92]
Fu, Z.; Qian, F.; Yang, X.; Jiang, H.; Chen, Y.; Liu, S. Circulating miR-222 in plasma and its potential diagnostic and prognostic value in gastric cancer. Med. Oncol., 2014, 31(9), 164.
[http://dx.doi.org/10.1007/s12032-014-0164-8] [PMID: 25129310]
[93]
Zhuang, K.; Han, K.; Tang, H.; Yin, X.; Zhang, J.; Zhang, X.; Zhang, L. Up-regulation of plasma miR-23b is associated with poor prognosis of gastric cancer. Med. Sci. Monit., 2016, 22, 356-361.
[http://dx.doi.org/10.12659/MSM.895428] [PMID: 26835790]
[94]
Zhang, W.H.; Gui, J.H.; Wang, C.Z.; Chang, Q.; Xu, S.P.; Cai, C.H.; Li, Y.N.; Tian, Y.P.; Yan, L.; Wu, B. The identification of miR-375 as a potential biomarker in distal gastric adenocarcinoma. Oncol. Res., 2012, 20(4), 139-147.
[http://dx.doi.org/10.3727/096504012X13522227232156] [PMID: 23461060]
[95]
Hung, P.S.; Chen, C.Y.; Chen, W.T.; Kuo, C.Y.; Fang, W.L.; Huang, K.H.; Chiu, P.C.; Lo, S.S. miR-376c promotes carcinogenesis and serves as a plasma marker for gastric carcinoma. PLoS One, 2017, 12(5), e0177346.
[http://dx.doi.org/10.1371/journal.pone.0177346] [PMID: 28486502]
[96]
Zhou, H.; Xiao, B.; Zhou, F.; Deng, H.; Zhang, X.; Lou, Y.; Gong, Z.; Du, C.; Guo, J. MiR-421 is a functional marker of circulating tumor cells in gastric cancer patients. Biomarkers, 2012, 17(2), 104-110.
[http://dx.doi.org/10.3109/1354750X.2011.614961] [PMID: 22263628]

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