Title:Biomarkers For the Diagnosis of Depression: Recent Updates
Volume: 19
Issue: 3
Author(s): Mikhil Santosh Kore and Kedar S. Prabhavalkar*
Affiliation:
- Department of Pharmacology, SVKM’s Dr. Bhanuben Nanavati College of Pharmacy, Mumbai-
400056, India
Keywords:
Biomarkers, depression, imaging biomarkers, transcriptomic, inflammatory biomarkers, neuroendocrine.
Abstract: Depression, or major depressive disorder, is a mental illness that significantly affects
psychosocial functioning and reduces the quality of one’s life. The annual incidence of depression
throughout the globe is around 6%. The disorder should be diagnosed at a particular stage
for the treatment to be designed. Biomarkers can help to do so with objective pieces of
evidence. Various biomarkers like Imaging biomarkers, Molecular biomarkers, Transcriptomic
biomarkers, Genetic biomarkers, Neuroendocrine, and Inflammatory biomarkers can be used to
diagnose depression. The use of digital sensors has also been reported recently for the determination
of depression. This review summarizes various biomarkers to diagnose depression.
Further recent updates and related clinical trials are included.