Title:Prediction of Cancer Treatment Using Advancements in Machine
Learning
Volume: 18
Issue: 3
Author(s): Arun Kumar Singh, Jingjing Ling*Rishabha Malviya*
Affiliation:
- Department of Good Clinical Practice, The Affiliated Wuxi Children's Hospital of Nanjing Medical
University, 299 Qingyang Road, 214023, Wuxi, P.R. China
- Department of Pharmacy, School of Medical and Allied Sciences, Galgotias University Greater Noida, Uttar
Pradesh, India
Keywords:
Cancer, therapy, patient care, machine learning, artificial intelligence, resistance.
Abstract: Many cancer patients die due to their treatment failing because of their disease's resistance
to chemotherapy and other forms of radiation therapy. Resistance may develop at any
stage of therapy, even at the beginning. Several factors influence current therapy, including
the type of cancer and the existence of genetic abnormalities. The response to treatment
is not always predicted by the existence of a genetic mutation and might vary for various
cancer subtypes. It is clear that cancer patients must be assigned a particular treatment or
combination of drugs based on prediction models. Preliminary studies utilizing artificial
intelligence-based prediction models have shown promising results. Building therapeutically
useful models is still difficult despite enormous increases in computer capacity due to the lack
of adequate clinically important pharmacogenomics data. Machine learning is the most widely
used branch of artificial intelligence. Here, we review the current state in the area of using
machine learning to predict treatment response. In addition, examples of machine learning
algorithms being employed in clinical practice are offered.