Title:Prevalence of Comorbidities of Psychotic Disorders in Patients
with Substance Use Disorders in Iran Psychiatric Hospital in
Tehran, Iran
Volume: 19
Issue: 3
Author(s): Shiva Soraya, Hamidreza Ahmad Khaniha and Afsaneh Aminpour*
Affiliation:
- Research Center of Addiction and Risky Behavior, Department of Psychiatry, School of Medicine,
Iran University of Medical Sciences, Tehran, Iran
Keywords:
Substance use disorder, psychotic disorders, comorbidity, epidemiological features, SCID, psychiatric hospital.
Abstract:
Background: Substance use disorders are highly prevalent among psychotic patients
and are associated with poorer clinical outcomes.
Objective: This study aimed to investigate the prevalence of psychotic disorders in substance
users and the epidemiological features of this population.
Materials and Methods: In a cross-sectional study, we investigated 455 outpatient and inpatient
participants with SUD referred to the Iran psychiatric hospital from April, 2020, to March,
2021. All participants were substance users, referred to Iran psychiatric center to follow up on
their comorbidities and psychiatric disorders. The Structured Clinical Interview for DSM-5
(SCID) was used for psychotic disorders and substance use disorder diagnoses. Finally, gathered
data were analyzed by SPSS-25.
Results: A total of 455 patients were involved in the study. The mean age was 34.66 years, of
which 89.7% were men. The most common main substances include methamphetamine
(39.1%) and heroin (27%). The prevalence of psychotic disorder was 36.7%, and the most
common type was substance-induced psychotic disorder (26.4%) and schizophrenia (8.4%).
There was a significant association between methamphetamine and opium use and the presence
of substance-induced psychotic disorder and schizophrenia, respectively (p ˂ 0.001).
Conclusion: The most common type of substance use was methamphetamine, and the most
common type of psychotic disorder was substance-induced psychotic disorder. There was a
significant association between methamphetamine and opium use and the presence of substance-
induced psychotic disorder and schizophrenia, respectively. It should be noted that this
was a sample of individuals hospitalized for substance abuse. It was not a general population
sample and was very biased toward substance use.
