Abstract
Amides are a critical class of widely distributed heterocycles in nature. The preparation of amides from benzoic acids and dicarbodiimides under catalyst-free conditions was reported. Various products were obtained in good to high yields. The model reaction could be scaled up to the gramscale level. A reaction mechanism was proposed based on control experiments and relevant literatures.
Keywords: Amides, benzoic acid, dicarbodiimide, catalyst-free conditions, reaction mechanism, benzoic acids.
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