Title:An Insight into Diverse Activities and Targets of Flavonoids
Volume: 24
Issue: 1
Author(s): Prashant Tiwari, Rakhi Mishra*, Avijit Mazumder, Rupa Mazumder and Ayushi Singh
Affiliation:
- Department of Pharmaceutical Chemistry, Noida Institute of Engineering and Technology (Pharmacy Institute),
Knowledge Park-2, Plot 19, Greater Noida, Uttar Pradesh, India
Keywords:
Flavonoids, targets, phytochemicals, medicinal plants, bioactive, secondary metabolites.
Abstract:
Background: Flavonoids belong to the chemical class of polyphenols and are in the category
of secondary metabolites imparting a wide protective effect against acute and chronic diseases.
Objective: The study aims to investigate and summarize the information of various flavonoids extracted,
isolated from various sources, and possess different pharmacological properties by acting
on multiple targets.
Methods: This comprehensive review summarizes the research information related to flavonoids
and their pharmacological action targets from various sources like PubMed, Google Scholar and
Google websites.
Results: Extracted information in the paper discusses various therapeutic effects of flavonoids isolated
from medicinal plant sources, which have the property to inhibit several enzymes, which finally
results in health benefits like anti-cancer, anti-bacterial, antioxidant, anti-allergic, and anti-viral
effects. This study also showed the different solvents and methods involved in the extraction and
characterization of the isolated phytochemical constituents.
Conclusion: The findings showed the contribution of several flavonoids in the management and inhibition
of various acute and chronic sicknesses by acting on different sites in the body. This study
may lead to gaining interest for more research on the bioactives of different medicinal plants for the
discovery of new lead compounds or further improvement of the efficacy of the existing compound.
