摘要
2型糖尿病(T2DM)是全球死亡和发病的主要原因之一。它会导致各种长期并发症,例如糖尿病肾病。糖尿病肾病是接受血液透析的慢性肾脏疾病患者肾衰竭的主要原因。因此,预防糖尿病肾病的发展和进展是2型糖尿病患者管理的主要目标之一。恩格列净的钠-葡萄糖共转运蛋白2抑制剂是一种有效的抗高血糖剂。此外,它已被证明具有一些药理学潜力,可为T2DM患者提供肾保护作用。在目前的研究中,我们从机制和分子的角度回顾了关于这种药物的潜在肾保护作用的现有临床数据。
关键词: 2型糖尿病,恩格列净,钠-葡萄糖共转运蛋白2抑制剂,慢性肾脏病,糖尿病肾病,肾保护作用。
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