Title:Echocardiography Parameters in Behcet’s Disease, A Comparative Study
Volume: 19
Issue: 2
Author(s): Reza Salehi Manzari, Zahra Mirfeizi*, Hoorak Poorzand*Zahra Abbasi Shaye
Affiliation:
- Rheumatic Diseases Research Center, Mashhad University of Medical Sciences, Mashhad, Iran
- Fellowship of Echocardiography, Vascular Surgery Research Center, Mashhad University of Medical Sciences, Mashhad, Iran
Keywords:
Behçet's disease (BD), echocardiography, systolic pulmonary artery pressure (sPAP), RHC, thrombosis.
Abstract:
Objective: Behçet's disease (BD) is a chronic inflammatory disease with multiple organ
involvements. Although cardiac involvement is not common, it can increase patient morbidity and
mortality and decrease life quality. In the present study, echocardiographic abnormalities in BD
with no cardiac symptoms were investigated.
Methods: This cross-sectional descriptive-analytic study was performed on patients referred to
Imam Reza Hospital in Mashhad from 2015 to 2018. The participants were divided into control and
BD groups. Patients with BD were diagnosed based on ISG criteria. All participants underwent
transthoracic echocardiography. Echocardiographic parameters were compared between BD and
control groups.
Results: In this study, the severity of aortic (AR), mitral (MR), and tricuspid valve regurgitation
(TR) was higher in BD than in the control group, while only TR severity showed a statistically significant
difference (p-value < 0.001). Systolic Pulmonary Artery Pressure (sPAP) was significantly
higher in BD compared to the control group (24.6 mmHg versus 22.81 mmHg, respectively) (pvalue
= 0.019).
Conclusion: It seems echocardiography is valuable in evaluating a cardiac function, even in asymptomatic
patients. Cases with moderate mitral and aortic regurgitation were only observed in BD.
Long-term follow-up is suggested, and further studies are required.
