Title:Hypertrophic Cardiomyopathy in Saudi Arabia: A Systematic Review of
the Epidemiological, Clinical, and Imaging Features
Volume: 19
Issue: 2
Author(s): Bodour S. Rajab*
Affiliation:
- Laboratory Medicine Department, Faculty of Applied Medical Sciences, Umm Al-Qura University, Makkah 24211,
Saudi Arabia
Keywords:
Hypertrophic, cardiomyopathy, dyspnea, epidemiological, imaging features, CVDs.
Abstract:
Background: A systematic review was performed to deliver a critical view of clinical
and research practice on hypertrophic cardiomyopathy (HCM) in Saudi Arabia. Scopus, PubMed,
and Google Scholar databases were searched for original articles reporting clinical and/or imaging
findings among HCM patients in Saudi Arabia. Of 559 records identified, 3 studies and 1 abstract
were included, involving 169 patients.
Methods: The mean age ranged between 40and 56 years, up to 93.3% were males. A family history
of HCM was reported in one study (5%), and sudden cardiac death was investigated in two studies
(9% and 13%). Dyspnea was the most frequent symptom (60-68.7%) reported, followed by
chest pain (12.5%-73.3%).
Results: Regarding complications, atrial fibrillation was reported among 0-25% of the patients, mitral
regurgitations among 13.3-50%, and ventricular tachycardia among 5-12.5%. Imaging parameters
were inadequately documented and suggested a high prevalence of left atrial enlargement, SVI
+ RV5 > 35 mm, blocks, and asymmetric septal hypertrophy.
Conclusion: The ejection fraction was reported by two studies with a mean±SD of 68±13% and
77.2±8.07%. The researchers stress the paucity, low quality, and disparity in time of original studies
about HCM in Saudi Arabia and recommend conducting national multicenter studies, with appropriate
design, notably using screening-based recruitment methods.
