Title:Regulatory Aspects, Types and Bioapplications of Metallic Nanoparticles:
A Review
Volume: 20
Issue: 7
Author(s): Shrutee Pawar and Anjali Takke*
Affiliation:
- Shobhaben Pratapbhai Patel School of Pharmacy and Technology Management, SVKM’s NMIMS, V. L. Mehta Road,
Vile Parle (W), Mumbai, India
Keywords:
Metallic nanoparticle, zinc, gold, silver, palladium, copper, iron, platinum.
Abstract:
Background: Nanotechnology is rapidly advancing in almost every area, such as the pharmaceutical
industry, food industry, nano fabrics, electronics, wastewater treatment, and agriculture.
Introduction: Metallic nanoparticles are commonly used in various fields but are especially important
in the pharmaceutical industry. Metallic nanoparticles have a size range of 10 nm to 100 nm.
Methods: Two techniques are used to synthesize metallic nanoparticles, the top-down approach and the
bottom-up approach. These techniques can be synthesized using three different methods: physical,
chemical, and biological. Chemical methods include coprecipitation, reduction, sonochemical, solvothermal,
and others, while physical methods include discharge, milling, and ion implantation. Biological
methods include plants and their extracts, agricultural wastes, microorganisms, and seaweeds.
Scanning electron microscopy, transmission electron microscopy, dynamic light scanning, and other
techniques are used to characterize them.
Results: All metallic nanoparticles are biocompatible and have special optical, electrical, magnetic, and
chemical properties. They are used in various industries, including the pharmaceutical industry as an
anticancer agent, antibacterial, antifungal, antioxidant, antidiabetic, and biosensors. Gold, silver, iron
oxide, zinc oxide, platinum, copper oxide, and palladium nanoparticles are the most common metal
nanoparticles used in the pharmaceutical industry. Monometallic and multimetallic nanoparticles are
broadly classified under this.
Conclusion: This article focuses on the major metallic nanoparticle groups, including synthesis, applications,
case studies, toxicity, regulatory aspects and innovative approaches to metallic nanomaterials.