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Mini-Reviews in Organic Chemistry

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ISSN (Print): 1570-193X
ISSN (Online): 1875-6298

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Mini-Review Article

Extraction Methods and Applications of Bioactive Compounds from Neem (Azadirachta indica): A Mini-Review

Author(s): Samuel Lepe de Alba, Conrado García-González*, Marcos A. Coronado Ortega, José R. Ayala Bautista, Gisela Montero Alpírez and Daniela G.L. Montes Núñez

Volume 20, Issue 7, 2023

Published on: 06 September, 2022

Page: [644 - 654] Pages: 11

DOI: 10.2174/1570193X19666220707125726

Price: $65

Abstract

Neem tree (Azadirachta indica), native to the Indian subcontinent, is known as a versatile plant, a rich source of bioactive compounds such as azadirachtin, nimonol, nimocinol, nimocinolide, gallic acid, gallocatechin, epicatechin, azadiradione, nimbin, salannin, epoxyazadiradione, etc. The isolated phytochemicals from neem, among others, are more than 300. The present work details the techniques for extracting compounds from different parts of neem, such as bark, husk seed, seed, seed oil, tree, leaves, and flowers. Furthermore, it comments on the various applications, including medicinal, environmental, and veterinary, of the neem-derived bioactive compounds, as well as their use in cattle raising and in cosmetics, disinfectants, rubber, and textile production, on the basis of a systematic documentary analysis from 2019 onwards.

Keywords: Neem, Azadirachta indica, extracts, applications of neem, azadirachtin, nimbin.

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Graphical Abstract

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