Title:Association between Red Blood Cell Distribution Width and Pulmonary
Function among Iranian Employees
Volume: 18
Issue: 4
Author(s): Hamidreza Pouragha, Tayebeh Nasiri Ardali, Ramin Mehrdad and Gholamreza Pouryaghoub*
Affiliation:
- Department of Occupational Medicine, School of Medicine, Center for Research on Occupational Diseases, Tehran University of Medical Sciences, Tehran, Iran
Keywords:
Red blood cell distribution width, respiratory function tests, screening approach, occupational health, pulmonary function, cardiovascular diseases.
Abstract:
Background: RDW has been proposed as a routine test and is available as a prognosis
for many diseases and disorders, especially respiratory disorders. In this study, we intend to see if
the association between pulmonary function and RDW also applies to non-patients.
Methods: This study was performed on 800 people including 466 women and 344 men. Participants
in the study were staff enrolled in the Tehran University of Medical Sciences cohort [TEC] study. In
this study, RDW levels and pulmonary function were assessed. Elderly populations were not included
in this study.
Results: The results of the univariate analysis showed that normal values versus abnormal values of
RDW were significantly associated with pulmonary function index FEV1, FVC, FEV1/FVC in nonpatient
individuals. On the other hand, a significant correlation was observed between RDW values
and FEV1 index and FEV1/FVC ratio. Based on linear regression, there was an association between
RDW and FVC [R2=0.721].
Conclusion: In this study, we found an association between RDW and FVC so we suggest that abnormal
RDW may be considered as a sign of pulmonary dysfunction.