Title:Prevalence of ABO Blood Grouping among Hemodialysis Patients in Dubai
Volume: 3
Author(s): Fakhriya Alalawi*, Kashif Gulzar, Waleed Mohamed Galaleldin and Amna Alhadari
Affiliation:
- Department of Nephrology, Dubai Hospital, Dubai Health Authority, Dubai, United Arab Emirates
Keywords:
ABO group, HD: hemodialysis, ESKD: End-Stage Kidney Disease, Mortality, Blood group phenotype, Diabetic nephropathy.
Abstract:
Background: Beyond their vital role in blood transfusion, ABO antigens were speculated to be involved in developing various human illnesses, including
infectious, neoplastic, cardiovascular, and many others. Many researchers attempted to highlight the relationship between kidney disease and ABO
phenotypes. The majority of these reports showed a predominance of blood group O antigen among patients with chronic kidney disease, while
few had opposed these findings. We aimed in this study to elaborate on blood group typing among our hemodialysis patients and whether it has a
prognostic effect on the overall mortality.
Methods: This is an observational, cross-sectional, retrospective study among chronic adult hemodialysis patients being dialyzed at Dubai Hospital over the
past six months, from Jan 2021 till June 2021. The patient's demographic characteristics (age, sex, etiology of chronic kidney disease, medical
comorbidities, and blood groups) were retrieved using an electronic hospital medical record system.
Results: Our study population constituted 224 hemodialysis patients; their mean age was 55.4 years (16-94 years), 83.6% were UAE nationals, and 59.8%
were males. Diabetic nephropathy was the etiology of end-stage kidney disease in 46%. ABO blood group distribution among our study population
was as follows; group O was the commonest (45%), followed by group B positive (23%) and A Positive (20.9%). Among the UAE national
patients group, O+ constitutes 46.9%, followed by B+ in 24%, and A+ in 21%. Nevertheless, group O+ was still the commonest among the nonnational
hemodialysis patients in 37.7%, A+ in 28.8%, and B+ in 24.4%. Additionally, group O-positive was the predominant group among all
diabetic dialysis patients (47%). Nine patients died during the study period of different causes; out of them, 4 patients (44.4%) had group O
positive.
Conclusion: Blood group O was the commonest blood group among our hemodialysis patients. Additionally, it was the commonest group in all diabetic dialysis
patients. More studies from Arab countries are needed to comprehend the relationship between ABO blood phenotypes and kidney disease and
whether certain blood groups have any role in a patient's progression to ESKD.
