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Current Cardiology Reviews

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ISSN (Print): 1573-403X
ISSN (Online): 1875-6557

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Stem Cells and Congenital Heart Disease: The Future Potential Clinical Therapy Beyond Current Treatment

Author(s): Katherine Julian*, Nikita Garg, Narutoshi Hibino and Rohit Jain

Volume 19, Issue 2, 2023

Published on: 29 August, 2022

Article ID: e310522205424 Pages: 4

DOI: 10.2174/1573403X18666220531093326

Price: $65

Abstract

Congenital heart disease (CHD) is the most common congenital anomaly in newborns. Current treatment for cyanotic CHD largely relies on the surgical intervention; however, significant morbidity and mortality for patients with CHD remain. Recent research to explore new avenues of treating CHD includes the utility of stem cells within the field. Stem cells have since been used to both model and potentially treat CHD. Most clinical applications to date have focused on hypoplastic left heart syndrome. Here, we examine the current role of stem cells in CHD and discuss future applications within the field.

Keywords: Stem cell, congenital heart disease, hypoplastic left heart, tissue engineering, regenerative medicine, cardiology.

Graphical Abstract

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