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Recent Advances in Food, Nutrition & Agriculture

Editor-in-Chief

ISSN (Print): 2772-574X
ISSN (Online): 2772-5758

Review Article

Antimicrobial, Pesticidal and Food Preservative Applications of Lemongrass Oil Nanoemulsion: A Mini-Review

Author(s): Deepika Balasubramanian, Agnishwar Girigoswami and Koyeli Girigoswami*

Volume 13, Issue 1, 2022

Published on: 28 June, 2022

Page: [51 - 58] Pages: 8

DOI: 10.2174/2212798412666220527154707

Price: $65

Abstract

Background: Essential oils that are extracted from plants have shown beneficial effects on humans and animals, evidenced by traditional medicine. They possess many essential phytocomponents that act as antimicrobial agents, and most of them are safe for external usage.

Introduction: Lemongrass essential oil is extracted from the grass, such as Cymbopogon flexuosus, and is used for antimicrobial activity for a long time. The efficacy of this oil is limited due to the poor solubility and microbial penetration, easy vaporization, and lower stability. Nanoformulations and nanoencapsulations are nanotechnology fields that aim to improve the bioavailability of many natural compounds and enhance their stability. Lemongrass oil has also been nanoformulated as nanoemulsion, and various antimicrobial activities against various pathogens have been demonstrated, which are superior to free lemongrass oil.

Methodology: We have used the search engines PubMed and Google Scholar for the mentioned keywords and selected the recent references related to this topic.

Conclusion: In this review, we have discussed various antimicrobial properties of lemongrass essential oil nanoemulsion and its application, such as antibacterial, antifungal, pesticidal, food preservative, and antibiofilm activity.

Keywords: Lemongrass, nanoemulsion, antimicrobial, pesticidal activity, food preservative, phytochemicals.

Graphical Abstract
[1]
Masoudzadeh SH, Mohammadabadi MR, Khezri A, et al. Dlk1 gene expression in different tissues of lamb. Iran J Appl Anim Sci 2020; 10: 669-77.
[2]
Masoudzadeh SH, Mohammadabadi M, Khezri A, et al. Effects of diets with different levels of fennel (Foeniculum vulgare) seed powder on DLK1 gene expression in brain, adipose tissue, femur muscle and rumen of Kermani lambs. Small Rumin Res 2020; 193: 106276.
[http://dx.doi.org/10.1016/j.smallrumres.2020.106276]
[3]
Mohammadabadi M, Masoudzadeh SH, Khezri A, et al. Fennel (Foeniculum vulgare) seed powder increases Delta-Like Non-Canonical Notch Ligand 1 gene expression in testis, liver, and humeral muscle tissues of growing lambs. Heliyon 2021; 7(12): e08542.
[http://dx.doi.org/10.1016/j.heliyon.2021.e08542] [PMID: 34917815]
[4]
Shahsavari M, Mohammadabadi M, Khezri A, et al. Correlation between insulin-like growth factor 1 gene expression and fennel (Foeniculum vulgare) seed powder consumption in muscle of sheep. Anim Biotechnol 2021; 1-11.
[http://dx.doi.org/10.1080/10495398.2021.2000997] [PMID: 34783639]
[5]
Eqbal A, Ansari VA, Hafeez A, Ahsan F, Imran M, Tanweer S. Recent applications of nanoemulsion based drug delivery system: A review. Res J Pharm Technol 2021; 14(5): 2852-8.
[http://dx.doi.org/10.52711/0974-360X.2021.00502]
[6]
Elkordy AA, Ahmad RRH, Awaad AS, Zak RM. An overview on natural product drug formulations from conventional medicines to nanomedicines: Past, present and future. J Drug Deliv Sci Technol 2021; 63: 102459.
[http://dx.doi.org/10.1016/j.jddst.2021.102459]
[7]
Cofelice M, Cinelli G, Lopez F, Di Renzo T, Coppola R, Reale A. Alginate-assisted Lemongrass (Cymbopogon nardus) essential oil dispersions for antifungal activity. Foods 2021; 10(7): 1528.
[http://dx.doi.org/10.3390/foods10071528] [PMID: 34359398]
[8]
Bakr OM, Zaghloul SS, Amer RI, Mostafa DAE, Bishbishy MHE. Formulation, characterization and antimicrobial efficacy of Aegle marmelos essential oil nanogel. Res J Pharm Technol 2021; 14(7): 3662-8.
[http://dx.doi.org/10.52711/0974-360X.2021.00633]
[9]
Heba SE, Bandar EA, Mahmoud AM, Hanan ME. Basic concepts of nanoemulsion and its potential application in pharmaceutical, cosmeceutical and nutraceutical fields. Res J Pharm Technol 2021; 14(7): 3938-6.
[http://dx.doi.org/10.52711/0974-360X.2021.00684]
[10]
Prasad LK, Hari K. Formulation and evaluation of solid self-nanoemulsifying drug delivery system for enhancing the solubility and dissolution rate of budesonide. Res J Pharm Technol 2021; 14(11): 5755-3.
[http://dx.doi.org/10.52711/0974-360X.2021.01001]
[11]
Majewska E, Kozłowska M, Gruczyńska-Sękowska E, Kowalska D, Tarnowska K. Lemongrass (Cymbopogon citratus) essential oil: Extraction, composition, bioactivity and uses for food preservation- A review. Pol J Food Nutr Sci 2019; 69(4): 327-41.
[http://dx.doi.org/10.31883/pjfns/113152]
[12]
Girigoswami A, Ghosh MM, Pallavi P, Seenuvasan R, Girigoswami K. Nanotechnology in detection of food toxins - Focus on the dairy products. Biointerface Res Appl Chem 2021; 11(6): 14155-72.
[http://dx.doi.org/10.33263/BRIAC116.1415514172]
[13]
Girigoswami K, Girigoswami A. A review on the role of nanosensors in detecting cellular mirna expression in colorectal cancer. Endocr Metab Immune Disord Drug Targets 2021; 21(1): 12-26.
[http://dx.doi.org/10.2174/1871530320666200515115723] [PMID: 32410567]
[14]
Metkar SK, Girigoswami K. Diagnostic biosensors in medicine- A review. Biocatal Agric Biotechnol 2019; 17: 271-83.
[http://dx.doi.org/10.1016/j.bcab.2018.11.029]
[15]
Girigoswami K, Akhtar N. 2019.http://www.ijnd.ir/article_660965.html
[16]
Thendral V, Dharshni T, Ramalakshmi M, Girigoswami A, Girigoswami K. Cerium oxide nanocluster based nanobiosensor for ROS detection. Biocatal Agric Biotechnol 2019; 19: 101124.
[http://dx.doi.org/10.1016/j.bcab.2019.101124]
[17]
De S, Gopikrishna A, Keerthana V, Girigoswami A, Girigoswami K. An Overview of Nano formulated Nutraceuticals and its therapeutic approaches. Curr Nutr Food Sci 2021; 17(4): 392-407.
[http://dx.doi.org/10.2174/1573401316999200901120458]
[18]
Ghosh S, Girigoswami K, Girigoswami A. Membrane-encapsulated camouflaged nanomedicines in drug delivery. Nanomedicine (Lond) 2019; 14(15): 2067-82.
[http://dx.doi.org/10.2217/nnm-2019-0155] [PMID: 31355709]
[19]
Sharmiladevi P, Breghatha M, Dhanavardhini K, Priya R, Girigoswami K, Girigoswami A. Efficient wormlike micelles for the controlled delivery of anticancer drugs. Nanosci Nanotechnol Asia 2021; 11(3): 350-6.
[http://dx.doi.org/10.2174/2210681210999200728115601]
[20]
Ojo OA, Olayide II, Akalabu MC, Ajiboye BO, Ojo AB, Oyinloye BE. Nanoparticles and their biomedical applications. Biointerface Res Appl Chem 2021; 11(1): 8431-45.
[http://dx.doi.org/10.33263/BRIAC111.84318445]
[21]
Krosuri PRK, Priyanka SN, Devi GA, Lakshmiprasanna S, Sujatha A, Akhila A. Formulation and evaluation of colon targeted drug delivery of diloxanide furoate tablets using pH dependent polymers. Res J Pharm Technol 2021; 14(11): 5959-4.
[http://dx.doi.org/10.52711/0974-360X.2021.01035]
[22]
Sharmiladevi P, Haribabu V, Girigoswami K, Sulaiman Farook A, Girigoswami A. Effect of mesoporous nano water reservoir on MR relaxivity. Sci Rep 2017; 7(1): 11179.
[http://dx.doi.org/10.1038/s41598-017-11710-2] [PMID: 28894269]
[23]
Sharmiladevi P, Akhtar N, Haribabu V, Girigoswami K, Chattopadhyay S, Girigoswami A. Excitation wavelength independent carbon-decorated ferrite nanodots for multimodal diagnosis and stimuli responsive therapy. ACS Appl Bio Mater 2019; 2(4): 1634-42.
[http://dx.doi.org/10.1021/acsabm.9b00039] [PMID: 35026897]
[24]
Haribabu V, Girigoswami K, Girigoswami A. Magneto-silver core-shell nanohybrids for theragnosis. Nano-Struct Nano-Objects 2021; 25: 100636.
[http://dx.doi.org/10.1016/j.nanoso.2020.100636]
[25]
Girigoswami A, Yassine W, Sharmiladevi P, Haribabu V, Girigoswami K. Camouflaged nanosilver with excitation wavelength dependent high quantum yield for targeted theranostic. Sci Rep 2018; 8(1): 16459.
[http://dx.doi.org/10.1038/s41598-018-34843-4] [PMID: 30405190]
[26]
Sharmiladevi P, Girigoswami K, Haribabu V, Girigoswami A. Nano-enabled theranostics for cancer. Adv Mater 2021; 2(9): 2876-91.
[http://dx.doi.org/10.1039/D1MA00069A]
[27]
Haribabu V, Girigoswami K, Sharmiladevi P, Girigoswami A. Water-nanomaterial interaction to escalate twin-mode magnetic resonance imaging. ACS Biomater Sci Eng 2020; 6(8): 4377-89.
[http://dx.doi.org/10.1021/acsbiomaterials.0c00409] [PMID: 33455176]
[28]
Vimaladevi M, Divya KC, Girigoswami A. Liposomal nanoformulations of rhodamine for targeted photodynamic inactivation of multidrug resistant gram negative bacteria in sewage treatment plant. J Photochem Photobiol B 2016; 162: 146-52.
[http://dx.doi.org/10.1016/j.jphotobiol.2016.06.034] [PMID: 27371913]
[29]
Heidarpour F, Mohammadabadi MR, Zaidul ISM, et al. Use of prebiotics in oral delivery of bioactive compounds: A nanotechnology perspective. Pharmazie 2011; 66(5): 319-24.
[PMID: 21699064]
[30]
Mohammadabadi MR, El-Tamimy M, Gianello R, Mozafari MR. Supramolecular assemblies of zwitterionic nanoliposome-polynucleotide complexes as gene transfer vectors: Nanolipoplex formulation and in vitro characterisation. J Liposome Res 2009; 19(2): 105-15.
[http://dx.doi.org/10.1080/08982100802547326] [PMID: 19242855]
[31]
Mohammadabadi MR, Mozafari MR. Enhanced efficacy and bioavailability of thymoquinone using nanoliposomal dosage form. J Drug Deliv Sci Technol 2018; 47(1): 445-53.
[http://dx.doi.org/10.1016/j.jddst.2018.08.019]
[32]
Mohammadabadi MR, Mozafari MR. Development of nanoliposome-encapsulated thymoquinone: Evaluation of loading efficiency and particle characterization. J Biopharm 2019; 11(4): 39-46.
[33]
Mohammadabadi MR. Applications and in vivo behaviour of lipid vesicles. Nanoliposomes From Fundamentals to Recent Developments. Canada: Trafford Publication 2005; pp. 67-76.
[34]
Zarrabi A, Alipoor Amro Abadi M, Khorasani S, et al. Nanoliposomes and tocosomes as multifunctional nanocarriers for the encapsulation of nutraceutical and dietary molecules. Molecules 2020; 25(3): 638.
[http://dx.doi.org/10.3390/molecules25030638] [PMID: 32024189]
[35]
Pieprzyca E, Skowronek R, Nižnanský Ľ, Czekaj P. Synthetic cathinones - From natural plant stimulant to new drug of abuse. Eur J Pharmacol 2020; 875: 173012.
[http://dx.doi.org/10.1016/j.ejphar.2020.173012] [PMID: 32087255]
[36]
Gago CML, Artiga-Artigas M, Antunes MDC, Faleiro ML, Miguel MG, Martín-Belloso O. Effectiveness of nanoemulsions of clove and lemongrass essential oils and their major components against Escherichia coli and Botrytis cinerea. J Food Sci Technol 2019; 56(5): 2721-36.
[http://dx.doi.org/10.1007/s13197-019-03762-1] [PMID: 31168154]
[37]
Masurkar SA, Chaudhari PR, Shidore VB, Kamble SP. Rapid biosynthesis of silver nanoparticles using Cymbopogan citratus (lemongrass) and its antimicrobial activity. Nano-Micro Lett 2011; 3(3): 189-94.
[http://dx.doi.org/10.1007/BF03353671]
[38]
Mishra D, Khare P, Singh DK, Luqman PV, Kumar A, Yadav A. Retention of antibacterial and antioxidant properties of lemongrass oil loaded on cellulose nanofibre-poly ethylene glycol. Ind Crops Prod 2018; 114: 68-80.
[http://dx.doi.org/10.1016/j.indcrop.2018.01.077]
[39]
Trujillo LS, Graü MAR, Fortuny RS, Belloso OM. Impact of microfluidization or ultrasound processing on the antimicrobial activity against Escherichia coli of lemongrass oil-loaded nanoemulsions. Food Control 2014; 3(1): 292-7.
[http://dx.doi.org/10.1016/j.foodcont.2013.09.015]
[40]
Prakash A, Baskaran R, Nithyanand P, Vadivel V. Effect of nanoemulsification on the antibacterial and anti-biofilm activities of selected spice essential oils and their major constituents against Salmonella enterica Typhimurium. J Cluster Sci 2020; 31(5): 1123-35.
[http://dx.doi.org/10.1007/s10876-019-01720-7]
[41]
Widyaningrum SA. Formulasi Dan Uji Aktivitas Antimikroba Nanoemulsi Minyak Manis-Jangan (Cinnamomum burmanni Nees ex BI) terhadap Pseudomonas aeruginosa NCTC 12924 dan Staphylococcus aureus ATCC 29213. Universitas Gajah Mada 2015.
[42]
Juniatik M, Hidayati K, Wulandari FP, Pangestuti N, Munawaroh N, Martien R. formulation of nanoemulsion mouthwash combination of lemongrass oil (cymbopogon citratus) and kaffir lime oil (Citrus hystrix) against candida albicans atcc 10231. Trad Med J 2017; 22(1): 7-1.
[http://dx.doi.org/10.22146/tradmedj.24255]
[43]
Gündel SDS, Godoi SND, Santos RCV, Silva JTD, Leite LBDM, Amaral AC. In vivo antifungal activity of nanoemulsions containing eucalyptus or lemongrass essential oils in murine model of Vulvovaginal candidiasis. J Drug Deliv Sci Technol 2020; 57: 101762.
[http://dx.doi.org/10.1016/j.jddst.2020.101762]
[44]
Sharma A, Sharma NK, Srivastava A, Kataria A, Dubey S, Sharma S. Clove and lemongrass oil based non-ionic nanoemulsion for suppressing the growth of plant pathogenic Fusarium oxysporumf.sp. lycopersici. Ind Crops Prod 2018; 123: 353-62.
[http://dx.doi.org/10.1016/j.indcrop.2018.06.077]
[45]
González MM, Zalazar AL, Pedreira JD, Campos CA, Gliemmo MF. Lemongrass and cinnamon oil nanoemulsions: Formulation and study of their physical stability and activity against Zygosaccharomyces bailii. Food Sci Technol Int 2021; 27(6): 485-98.
[http://dx.doi.org/10.1177/1082013220969100] [PMID: 34487460]
[46]
Gago C, Antão R, Dores C, et al. The effect of nanocoatings enriched with essential oils on ‘rocha’ pear long storage. Foods 2020; 9(2): 240.
[http://dx.doi.org/10.3390/foods9020240] [PMID: 32102293]
[47]
Kim IH, Lee H, Kim JE, et al. Plum coatings of lemongrass oil-incorporating carnauba wax-based nanoemulsion. J Food Sci 2013; 78(10): E1551-9.
[http://dx.doi.org/10.1111/1750-3841.12244] [PMID: 24024904]
[48]
Mendes JF, Norcino LB, Martins HH, et al. Development of quaternary nanocomposites made up of cassava starch, cocoa butter, lemongrass essential oil nanoemulsion, and brewery spent grain fibers. J Food Sci 2021; 86(5): 1979-96.
[http://dx.doi.org/10.1111/1750-3841.15689] [PMID: 33822378]
[49]
Maherani B, Harich M, Salmieri S, Lacroix M, Salmieri S, Lacroix M. Antibacterial properties of combined non-thermal treatments based on bioactive edible coating, ozonation, and gamma irradiation on ready-to-eat frozen green peppers: evaluation of their freshness and sensory qualities. Eur Food Res Technol 2019; 245(5): 11095-111.
[http://dx.doi.org/10.1007/s00217-018-3211-4]
[50]
Kim IH, Oh YA, Lee H, Song BK, Min SC. Grape berry coatings of lemongrass oil-incorporating nanoemulsion. Lebensm Wiss Technol 2014; 58(1): 1-10.
[http://dx.doi.org/10.1016/j.lwt.2014.03.018]
[51]
Oh YH, Oh YJ, Song AY, Won JS, Song BK, Min SC. Comparison of effectiveness of edible coatings using emulsions containing lemongrass oil of different size droplets on grape berry safety and preservation. Lebensm Wiss Technol 2017; 75: 742-50.
[http://dx.doi.org/10.1016/j.lwt.2016.10.033]
[52]
Azarakhsh N, Osman A, Ghazali HM, Tan CP, Adzahan NM. Lemongrass essential oil incorporated into alginate-based edible coating for shelf-life extension and quality retention of fresh-cut pineapple. Postharvest Biol Technol 2014; 88: 1-7.
[http://dx.doi.org/10.1016/j.postharvbio.2013.09.004]
[53]
Saada NS, Maksoud GA, Aziz MSAE, Youssef AM. Evaluation and utilization of lemongrass oil nanoemulsion for disinfection of documentary heritage based on parchment. Biocatal Agric Biotechnol 2020; 29: 101839.
[http://dx.doi.org/10.1016/j.bcab.2020.101839]
[54]
Velho MC, Cossetin LF, Godoi SND, Santos RCV, Gündel AA, Monteiro SG. Nanobiopesticides: Development and insecticidal activity of nanoemulsion containing lemongrass or eucalyptus oils. Nat Prod Res 2020; 35(24): 1-6.
[http://dx.doi.org/10.1080/14786419.2020.1837809] [PMID: 33307816]
[55]
Rossi GG, Guterres KB, Bonez PC, et al. Antibiofilm activity of nanoemulsions of Cymbopogon flexuosus against rapidly growing mycobacteria. Microb Pathog 2017; 113: 335-41.
[http://dx.doi.org/10.1016/j.micpath.2017.11.002] [PMID: 29122674]
[56]
da Silva Gündel S, de Souza ME, Quatrin PM, et al. Nanoemulsions containing Cymbopogon flexuosus essential oil: Development, characterization, stability study and evaluation of antimicrobial and antibiofilm activities. Microb Pathog 2018; 118: 268-76.
[http://dx.doi.org/10.1016/j.micpath.2018.03.043] [PMID: 29581028]

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